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Nasal formulations for drug administration and characterization of nasal preparations in drug delivery.

Therapeutic delivery, 2020
This special report gives an insight in the rationale of utilizing the nasal cavity for drug administration and the formulation as well as characterization of nasal preparations.
R. Scherließ
semanticscholar   +1 more source

Drug Administration Schedules

American Journal of Psychiatry, 1969
Common current practice is to prescribe psychotropic drugs so that a specified daily amount is administered in equally divided doses on a three to six times a day schedule. The authors contend that this procedure rests on no valid scientific basis.
A, Dimascio, R I, Shader
openaire   +3 more sources

Intracerebroventricular Administration of Drugs

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2009
Intracerebroventricular drug administration is a method that bypasses the blood‐brain barrier and other mechanisms that limit drug distribution into the brain, allowing high drug concentrations to enter the central compartment. Instillation of drugs directly into the ventricles of the brain must be done carefully and with full consideration of factors ...
Aaron M, Cook   +4 more
openaire   +2 more sources

Intrathecal administration of drugs

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2016
The article summarizes the introduction of drugs into the cerebrospinal fluid. Indications and contraindications for the administration of pharmaceuticals in the cerebrospinal fluid spaces are presented. Main groups of pharmacological agents used for endolumbar introduction and conditions under which they are used, as well as advantages and ...
I A, Lebedev   +4 more
openaire   +2 more sources

A 25-Year Experience of US Food and Drug Administration Accelerated Approval of Malignant Hematology and Oncology Drugs and Biologics: A Review

JAMA Oncology, 2018
Importance Accelerated approval (AA) is a US Food and Drug Administration (FDA) expedited program intended to speed the approval of drugs and biologics that may demonstrate a meaningful advantage over available therapies for diseases that are serious or ...
J. Beaver   +11 more
semanticscholar   +1 more source

Drug interactions and multiple drug administration

Clinical Pharmacology & Therapeutics, 1977
Effects of multiple drug administration on adverse drug reactions were studied in 10,518 patients hospitalized on a general medical service during a five‐year period. Nine index drug groups, including analgesic, antacid, antiarrhythmic, antimicrobic, anticoagulant, antihypertensive, anti‐inflammatory, diuretic, and sedative‐tranquilizer drugs, were ...
F E, May, R B, Stewart, L E, Cluff
openaire   +2 more sources

Transcutaneous drug administration

, 2020
The first part of this chapter focuses on the benefits and limitations of transdermal drug delivery systems (TDDSs). Advantages include convenience, avoidance of presystemic metabolism (first-pass effect) and painlessness.
K. Ita
semanticscholar   +1 more source

Drug administration in custody

Journal of Clinical Forensic Medicine, 1999
This paper describes the system for drug administration to prisoners in custody which has been developed at U Division, Kilmarnock in Strathelyde. The protocols agreed by the police surgeons in the area are described. The system is relevant to all police surgeons in their daily work, particularly with the advent of general practice cooperatives and the
openaire   +2 more sources

Drug administration

Antenatal Midwifery Skills, 2020
A. Edwards
openaire   +2 more sources

Drug administration

2010
By the end of this chapter you will be introduced to the concepts of pharmacokinetics and pharmacodynamics with specific emphasis on the infant, child, and young person. You will be presented with the current evidenced- based practice in relation to differing routes of drug administration in children and young people, underpinned by a firm rationale ...
Carol Barron, Eleanor Hollywood
openaire   +1 more source

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