Results 261 to 270 of about 577,363 (331)

Polymer-drug conjugates: recent progress on administration routes

Expert Opinion on Drug Delivery, 2014
Polymer-drug conjugates are an important part of polymer therapeutics. Recently, they have been used as an appealing platform for drug delivery. As a delivery vector, the route of administration performs a serious impact on the accessibility of drug molecules to their respective target site and therapeutic index.
Guangxi Zhai, Xiaoye Yang, Xin Pang
openaire   +4 more sources

Parenteral Drug Administration: Routes of Administration and Devices

Parenteral Medications, 2012
Laura A. Thoma, Himanshu Bhattacharjee, Vivian S. Loveless   +2 more
semanticscholar   +4 more sources

Routes of Drug Administration

2018
Systemic absorption of a drug depends on its physicochemical properties, the nature of the dosage form on which it is included and the anatomical and physiological characteristics of the site of absorption. These considerations are important on the biopharmaceutical production and evaluation of drugs: the design of the dosage forms requires a deep ...
María Esperanza Ruiz, María Esperanza Ruiz, Sebastián Scioli Montoto   +2 more
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Route of administration and drug metabolism

European Journal of Pharmacology, 1972
Abstract Studies with ‘first-pass’ pharmacokinetic models have revealed a number of interesting characteristics in regard to the influence of route of administration on drug and metabolite levels in the tissue, the % of dose excreted in the urine as unchanged drug and the composition of total metabolites in the urine.
S. Feldman, S. Feldman, M. Gibaldi, M. Gibaldi   +3 more
openaire   +3 more sources

Route of Administration and Drug Disposition

Drug Metabolism Reviews, 1975
(1975). Route of Administration and Drug Disposition. Drug Metabolism Reviews: Vol. 3, No. 1, pp. 185-199.
Milo Gibaldi, Donald Perrier
openaire   +3 more sources

Routes of Drug Administration

2007
Historical review of routes of drug administration Baggellardus, a contemporary of Columbus, observed Indians applying fumigation to the mouth or anus of apparently dead persons and brought the technique to Europe. In the aftermath, during the seventeenth and eighteenth century, scientific societies all over Europe recommended warmth, artificial ...
Thomas Kerz, Holger Herff, Gideon Paret
openaire   +4 more sources

Effect of route of administration on drug disposition

Journal of Pharmacokinetics and Biopharmaceutics, 1972
An increasing body of information tends to support the hypothesis that drug effect, therapeutic or toxic, is more closely correlated with plasma concentration than dose (Levy, 1968). Absorption is one important determinant of drug plasma levels. Distribution and elimination are others.
Malcolm Rowland, Sidney Riegelman
openaire   +3 more sources

Topical drug delivery to the retina: obstacles and routes to success

Expert Opinion on Drug Delivery, 2021
Introduction Retinal diseases are one of the main reasons for vision loss where all available drug treatments are based on invasive drug administration such as intravitreal injections.
T. Loftsson
semanticscholar   +1 more source

Formulating SLN and NLC as innovative drug delivery systems for non-invasive routes of drug administration.

Current Medicinal Chemistry, 2019
Colloidal carriers diverge depending on their composition, ability to incorporate drugs and applicability, but the common feature is the small average particle size. Among the carriers with the potential nanostructured drug delivery application there are
B. Fonseca-Santos, P. B. Silva, R. Rigon, M. R. Sato, M. Chorilli   +4 more
semanticscholar   +1 more source

Drug Absorption and Routes of Administration

1988
We will deal here with the process of drug absorption from different sites in the body. Drug absorption, whether it be from the gastro-intestinal tract or from the buccal mucosa, requires the passage of the drug in a molecular form across the barrier membrane.
D. Attwood, A. T. Florence
openaire   +2 more sources