Results 71 to 80 of about 101,859 (303)

Parenteral systems for statin delivery: a review

Lipids in Health and Disease, 2019
The oral route of drug administration is the most common and convenient route for dosing statin drugs, and, in fact, most medications, because of ease of drug delivery, patient compliance, and cost-effectiveness.
Shahla Korani, Samira Bahrami, Mitra Korani, Maciej Banach, Thomas P. Johnston, Amirhossein Sahebkar   +5 more
doaj   +1 more source

Extracellular Vesicles as Drug Carriers for Enzyme Replacement Therapy to Treat CLN2 Batten Disease: Optimization of Drug Administration Routes

, 2021
Matthew J. Haney, Y. Zhao, Y.S. Jin, E.V. Batrakova   +3 more
openalex   +1 more source

Durable Physically Mixed Microporous and Mesoporous MOFs/Nanofiber Aerogel 3D Composites for Effective Toxic Gas Capture and Organophosphonate Detoxification

Advanced Functional Materials, EarlyView.
Ultralight 3D nanofibrous aerogels embedded with metal‐organic frameworks effectively capture and neutralize toxic gases and organophosphonates. Incorporating mesoporous UiO‐66‐NH2 and HKUST‐1 into PAN/PVP fibers enables high MOF loading while maintaining mechanical strength and structural stability.
Mai O. Abdelmigeed, Muhammed Ziauddin Ahmad Ebrahim, John J. Mahle, Brandon B. Blount, Gregory W. Peterson, Saad A. Khan, Gregory N. Parsons   +6 more
wiley   +1 more source

Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system

Frontiers in Pharmacology
BackgroundArrhythmias are prevalent cardiac disorders with significant impacts on patient quality of life and mortality. Amiodarone, a class III antiarrhythmic agent, is widely used to manage both atrial and ventricular arrhythmias due to its efficacy in
Jingrong Yang, Mengfan You, Jingxin Wang, Rongfei Sun, Lili Han, Xiaonan Liu, Kaibin Niu, Kaidi Xing, Juanping Sun, Wenge Su, Yifei Wang   +10 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Unusual Swelling Behavior of Hydrogels Modified with Spiropyran as Appendage or Crosslinker

Advanced Functional Materials, EarlyView.
Not so innocent after all—spiropyran crosslinkers in methylenebisacrylamide‐crosslinked poly(acrylamide‐co‐acrylic acid) hydrogels increase crosslinking density, but also, counterintuitively, increase swelling. Charge complexation, cooperative chemo‐mechanical effects, and aggregation may explain these observations.
Michael M. Lerch, Ankita Shastri, Thomas B. H. Schroeder, Amos Meeks, Shucong Li, Anna V. Shneidman, Michael Aizenberg, Joanna Aizenberg   +7 more
wiley   +1 more source

Solid lipid nanoparticles the emerging approach in pharmaceuticals: An overview

Al-Mustansiriyah Journal of Pharmaceutical Sciences
In recent years, great attention has been attentive to lipid-based drug delivery systems to concur with limitations associated with conventional formulations.
Iman Sabah Jaafar, Methaq Hamad Sabar, Noor Sabah Jaafar   +2 more
doaj   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Advances in Allergen Immunotherapy and Safety

Vaccines
Allergen immunotherapy (AIT) modifies immune responses to treat allergies. AIT treatment is a 3-month to 3-year long-term strategy, and its potential candidates are allergic rhinitis and asthma, food allergy, and insect venom allergy.
Samia T. Al-Shouli
doaj   +1 more source

Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: do not confound access route and specific drug complications!

, 2021
Romain Jouffroy, Benoît Vivien
openalex   +1 more source