Results 121 to 130 of about 4,129,851 (352)

Diagnosing and managing drug allergy

Canadian Medical Association Journal, 2018
KEY POINTS Adverse drug reactions are common both in outpatient and inpatient settings. A meta-analysis of 39 prospective studies from American hospitals that was published in 1998 reported an incidence of serious adverse drug reactions of 6.7% and fatal
E. Abrams, D. Khan
semanticscholar   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Steroids in pediatric eosinophilic esophagitis [PDF]

, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

Advanced Materials Interfaces, EarlyView.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu   +7 more
wiley   +1 more source

Cephalosporin Induced Toxic Epidermal Necrolysis and Subsequent Penicillin Drug Exanthem

Allergology International, 2008
Background: Drug hypersensitivity is classically divided into IgE mediated and non-IgE mediated disease. We report a rare case of consequent IgE mediated and non-IgE mediated reactions within the beta lactam class of antibiotics. Case Summary: An 84-year-
Amanda Lam, Inderpal Randhawa, William Klaustermeyer   +2 more
doaj   +1 more source

Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings

Advanced Therapeutics, EarlyView.
Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy, Kubra Sener, M. Burcu Külahci, K. Barbaros Balabanli, Şule Coşkun Cevher   +4 more
wiley   +1 more source

Beta-lactam allergy in Chinese patients and factors predicting genuine allergy

World Allergy Organization Journal, 2019
Introduction: Beta-lactams (BL) are the most frequently reported drug allergy, but the vast majority of patients are found not to be genuinely allergic after evaluation. Few studies have investigated the clinical predictors of genuine BL allergy, and the
Philip Hei Li, Leonard Quok Chean Siew, Iason Thomas, Timothy J. Watts, Kok Loong Ue, Krzysztof Rutkowski, Chak-Sing Lau   +6 more
doaj  

Galactose-α-1,3-galactose Allergy Induced by Amblyomma americanum: A Review and Introduction of Experimental Designs [PDF]

, 2017
The galactose-α-1,3-galactose (alpha-gal) allergy was identified following a drug trial of Cetuximab. The patients who reacted with anaphylaxis had all previously been bitten by the lone star tick.
Gasterland, Brianna
core