Results 291 to 300 of about 4,150,951 (316)

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

open access: yesAnimal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao   +6 more
wiley   +1 more source

Recognition of Glycine Versus Nonglycine Citrulline Motifs Dictating the HLA Class II Association of Anticitrullinated Protein Antibodies: Insights From Autoantibody Profiling of 6,900 Scandinavian Patients With Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm   +18 more
wiley   +1 more source

Regulation of Chondrocyte Metabolism and Osteoarthritis Development by Sirt5 Through Protein Lysine Malonylation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu   +11 more
wiley   +1 more source

Recurrence Risk in Pediatric Noninfectious Uveitis During Adalimumab Tapering: An International Multicenter Retrospective Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study aims to assess the risk of noninfectious uveitis (NIU) relapse in pediatric patients undergoing adalimumab (ADA) tapering, evaluating potential predictors of such risk. Methods We conducted a multicenter retrospective cohort study involving pediatric patients with NIU who underwent ADA tapering due to inactive uveitis.
Achille Marino   +31 more
wiley   +1 more source

The Inflation Reduction Act and Etanercept

open access: yes
Arthritis &Rheumatology, EarlyView.
Charles L. Bennett   +6 more
wiley   +1 more source

Female sex as a risk factor for penicillin drug allergy in the inpatient setting.

Allergy and Asthma Proceedings, 2022
Background: Penicillin is the most common reported drug allergy. Previous literature suggests that there is increased prevalence of penicillin drug allergy in female patients in the outpatient setting.
D. Voelker   +2 more
semanticscholar   +1 more source

Prevalence of drug allergy in South Australia

Internal medicine journal (Print), 2021
Drug allergy is commonly reported in patient notes and electronic health records. The prevalence of self‐reported drug allergy in the general Australian population has not previously been studied.
C. Yuson, S. Shakib, William B Smith
semanticscholar   +1 more source

Drug allergy management in the elderly

Current Opinion in Allergy and Clinical Immunology, 2021
Purpose of review Drug allergy management has previously not been emphasized in the elderly. However, the geriatric population poses several unique characteristics, challenges for drug allergy testing and considerations in the management.
Jane C Y Wong, P. Li
semanticscholar   +1 more source

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