Results 31 to 40 of about 3,877,679 (249)

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Feasibility of a drug allergy registry-based excipient allergy database and call for universal mandatory drug ingredient disclosure: the case of PEG

open access: yesFrontiers in Allergy
BackgroundExcipient allergy is a rare, but potentially lethal, form of drug allergy. Diagnosing excipient allergy remains difficult in regions without mandatory drug ingredient disclosure and is a significant barrier to drug safety.ObjectiveTo ...
Andy Ka Chun Kan   +4 more
doaj   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

open access: yesFEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

Screening for penicillin allergy in obstetric patients to optimize guideline directed therapy

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Objective: To assess the safety of penicillin allergy evaluation and testing in obstetric patients utilizing oral drug challenges with or without prior penicillin skin testing (PST) depending on characteristics of the patient’s medication reaction, and ...
Kayla Godfrey   +5 more
doaj   +1 more source

Overview of Drug Allergy: From Immunogenetic Basis to Practice

open access: yesActa Médica Portuguesa, 2018
Drug therapy is often a balance between the beneficial and harmful effects of drugs. Drug allergic reactions are adverse reactions mediated by immunological mechanisms and usually not related to the pharmacological actions of the drug.
Eunice Dias de Castro   +3 more
doaj   +1 more source

Prevalence of Asthma and Allergic Diseases Among Children in Adıyaman, Türkiye: a Cross-sectional Study

open access: yesÇocuk Dergisi, 2023
Objective: To determine the prevalence and associated risk factors of asthma and allergic diseases in school children and adolescents in Adıyaman, Turkey.
Velat Çelik   +3 more
doaj   +1 more source

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin   +10 more
wiley   +1 more source

Retrospective Examınatıon of Children with Beta Lactam-Drug Allergy: A Single-Center Experience

open access: yesÇocuk Dergisi
Objective: The occurrence of drug reactions due to IgE or T-cell-mediated hypersensitivity reactions is referred to as drug allergy. Beta-lactam antibiotic (BLA) is the most common cause of drug allergy.
Şeyma Dilek, Deniz Özçeker
doaj   +1 more source

Drug allergy evaluation in children with suspected mild antibiotic allergy

open access: yesFrontiers in Allergy, 2022
BackgroundAdverse antibiotic reactions caused by an immunological mechanism are known as allergic reactions. The percentage of reported antibiotic allergies is likely to differ from the one validated after a drug provocation test (DPT) with the culprit ...
Nikolaos Kitsos   +7 more
doaj   +1 more source

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