Results 51 to 60 of about 4,129,851 (352)

Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]

, 2016
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA, DUSE, MARZIA, Laitano, Rossella, LEONARDI, LUCIA   +3 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Allergic disorders and their risk factors in primary Sjögren's syndrome

World Allergy Organization Journal, 2023
Objective: This study aimed to evaluate the prevalence of allergic disorders in patients with primary Sjögren's syndrome (pSS), compare it with that of patients with rheumatoid arthritis (RA), and examine the risk factors in patients with pSS.
Misako Higashida-Konishi, MD, PhD, Keisuke Izumi, MD, PhD, Tatsuya Shimada, MD, Satoshi Hama, MD, Tatsuhiro Oshige, MD, Hisaji Oshima, MD, PhD, Yutaka Okano, MD, PhD   +6 more
doaj  

Kounis Syndrome Associated With Selective Anaphylaxis to Cefazolin. [PDF]

, 2018
info:eu-repo/semantics ...
Chambel, M, Correia, M, Gaspar, A, Morais-Almeida, M, Mota, I, Sequeira, T   +5 more
core   +1 more source

Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels. Methods Patients with FIRES admitted to the Intensive Care Unit (ICU) of Beijing Children's Hospital were retrospectively ...
Yushan He, Jie Wu, Chaonan Fan, Zheng Li, Jun Liu, Kechun Li, Quan Wang, Suyun Qian   +7 more
wiley   +1 more source

Overview of Drug Allergy: From Immunogenetic Basis to Practice

Acta Médica Portuguesa, 2018
Drug therapy is often a balance between the beneficial and harmful effects of drugs. Drug allergic reactions are adverse reactions mediated by immunological mechanisms and usually not related to the pharmacological actions of the drug.
Eunice Dias de Castro, Fabrícia Carolino, Laura Ribeiro, Josefina R. Cernadas   +3 more
doaj   +1 more source

Prevalence of Asthma and Allergic Diseases Among Children in Adıyaman, Türkiye: a Cross-sectional Study

Çocuk Dergisi, 2023
Objective: To determine the prevalence and associated risk factors of asthma and allergic diseases in school children and adolescents in Adıyaman, Turkey.
Velat Çelik, Hüseyin Tanrıverdi, Fedli Emre Kılıç, Tolga Tutal   +3 more
doaj   +1 more source

Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials

Arthritis Care &Research, EarlyView.
Objective Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.
Jemma Hudson, Mari Imamura, Clare Robertson, Daniel Whibley, Lorna Aucott, Katie Gillies, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole K. Y. Tang, Gary J. Macfarlane, Miriam Brazzelli   +11 more
wiley   +1 more source

Screening for penicillin allergy in obstetric patients to optimize guideline directed therapy

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: To assess the safety of penicillin allergy evaluation and testing in obstetric patients utilizing oral drug challenges with or without prior penicillin skin testing (PST) depending on characteristics of the patient’s medication reaction, and ...
Kayla Godfrey, Deanna McDanel, Kelly Percival, Noelle Bowdler, Donna Santillan, Amy Dowden   +5 more
doaj   +1 more source

Prealbumin epitópok haptén hordozó szerepének vizsgálata limfocita transzformációs tesztben a gyógyszerallergia igazolására = The role of prealbumin as a hapten-carrier protein in lymphocyte transformation test for the establishment of drug allergy [PDF]

, 2008
Korábbi vizsgálataink alapján célul tűztük ki, hogy megvizsgáljuk a prealbumin egyes szerkezeti elemeinek haptén hordozó szerepét és különböző gyógyszerekhez kapcsolva nagyszámú betegben meghatározzuk, növelhető-e a limfocita transzformációs teszt (LTT ...
Bohácsné dr. Altmayer, Anita, Husz, Sándor, Kenderessy Szabó, Anna, Kis, Kornélia, Kiss, Mária, Mihályi, Lilla, Tóth, Gábor   +6 more
core