Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized trial enrolled infants aged 2–14 months with new‐onset IESS, randomly assigned them (1:1) to receive either
Rachata Boonkrongsak +6 more
wiley +1 more source
Drug allergy and the risk of lymph node metastasis in rectal cancer. [PDF]
PLoS ONE, 2014 Previous epidemiologic studies have reported that a history of allergy is associated with reduced risk of colorectal cancer and other malignancies.
Chun Gao +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Despite knowledge that health outcomes vary according to patient characteristics, identity, and geography, including underrepresented populations in arthritis research remains a challenge. We conducted interviews to explore how researchers in arthritis have used equity, diversity, and inclusion (EDI) principles to inform their research ...
Megan M. Thomas +8 more
wiley +1 more source
Detecting drug-drug interactions using artificial neural networks and classic graph similarity measures [PDF]
, 2019 Drug-drug interactions are preventable causes of medical injuries and often result in doctor and emergency room visits. Computational techniques can be used to predict potential drug-drug interactions. We approach the drug-drug interaction prediction problem as a link prediction problem and present two novel methods for drug-drug interaction prediction
arxiv +1 more source
Knowledge-Driven New Drug Recommendation [PDF]
arXiv, 2022 Drug recommendation assists doctors in prescribing personalized medications to patients based on their health conditions. Existing drug recommendation solutions adopt the supervised multi-label classification setup and only work with existing drugs with sufficient prescription data from many patients.
arxiv
Switching patients from other inhaled corticosteroid devices to the Easyhaler(®) : historical, matched-cohort study of real-life asthma patients [PDF]
, 2014 Peer reviewedPublisher ...
Gould, Shuna +5 more
core +1 more source
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Arthritis Care &Research, EarlyView.Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp +6 more
wiley +1 more source
Semi-Supervised Hierarchical Drug Embedding in Hyperbolic Space [PDF]
arXiv, 2020 Learning accurate drug representation is essential for tasks such as computational drug repositioning and prediction of drug side-effects. A drug hierarchy is a valuable source that encodes human knowledge of drug relations in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target ...
arxiv
Prealbumin epitópok haptén hordozó szerepének vizsgálata limfocita transzformációs tesztben a gyógyszerallergia igazolására = The role of prealbumin as a hapten-carrier protein in lymphocyte transformation test for the establishment of drug allergy [PDF]
, 2008 Korábbi vizsgálataink alapján célul tűztük ki, hogy megvizsgáljuk a prealbumin egyes szerkezeti elemeinek haptén hordozó szerepét és különböző gyógyszerekhez kapcsolva nagyszámú betegben meghatározzuk, növelhető-e a limfocita transzformációs teszt (LTT ...
Bohácsné dr. Altmayer, Anita +6 more
core
What We Mean When We Talk About Adherence In Respiratory Medicine [PDF]
, 2016 The Respiratory Effectiveness Group (REG; www.effectivenessevaluation.org) supported the Expert Adherence Panel Meeting at which many of the concepts presented in this paper were first discussed. REG also supported the manuscript submission costs.
Chisholm, Alison +8 more
core +5 more sources