Results 231 to 240 of about 2,834,658 (290)

Antiepileptic Drug Combinations for Epilepsy: Mechanisms, Clinical Strategies, and Future Prospects. [PDF]

Int J Mol Sci
Li C, Wang X, Deng M, Luo Q, Yang C, Gu Z, Lin S, Luo Y, Chen L, Li Y, He B.   +10 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Assessment of pharmacodynamic interactions of two-drug combinations of five selected cytostatics in an in vitro model of human melanoma: an isobolographic analysis. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Wróblewska-Łuczka P, Góralczyk A, Łuszczki JJ.   +2 more
europepmc   +1 more source

A Machine Learning-Based Strategy Predicts Selective and Synergistic Drug Combinations for Relapsed Acute Myeloid Leukemia. [PDF]

Cancer Res
Chen Y, He L, Ianevski A, Nader K, Ruokoranta T, Linnavirta N, Miettinen JJ, Vähä-Koskela M, Vänttinen I, Kuusanmäki H, Kontro M, Porkka K, Wennerberg K, Heckman CA, Giri AK, Aittokallio T.   +15 more
europepmc   +1 more source

Drug Combinations Targeting FAK and MEK Overcomes Tumor Heterogeneity in Glioblastoma. [PDF]

Pharmaceutics
Furqan M, Elliott RJR, Nagle PWK, Dawson JC, Masalmeh R, Garcia VA, Munro AF, Drake C, Morrison GM, Pollard SM, Ebner D, Brunton VG, Frame MC, Carragher NO.   +13 more
europepmc   +1 more source

Statistical innovations in clinical trial design with a focus on drug combinations, factorials, and other multiple therapy issues. [PDF]

J Prev Alzheimers Dis
Berry DA.
europepmc   +1 more source

Flash optimization of drug combinations for Acinetobacter baumannii with IDentif.AI-AMR. [PDF]

NPJ Antimicrob Resist
You K, Binte Mohamed Yazid N, Chong LM, Hooi L, Wang P, Zhuang I, Chua S, Lim E, Kok AZX, Marimuthu K, Vasoo S, Ng OT, Chan CEZ, Chow EK, Ho D.   +14 more
europepmc   +1 more source

HIG-Syn: a hypergraph and interaction-aware multigranularity network for predicting synergistic drug combinations. [PDF]

Bioinformatics
Gu Y, Zu J, Sun Y, Zhang L.
europepmc   +1 more source

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Combination Drug Therapy

Journal of the American Medical Directors Association, 2005
Caring for the elderly nursing home patient has never been more clinically complex or administratively more troublesome. Patients carry with them a greater burden of disease with increasing frailty and vulnerability. More drugs are being used for more problems.
Eric G, Tangalos, Barbara J, Zarowitz
openaire   +2 more sources