Results 261 to 270 of about 943,135 (348)

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Protocol to calculate the synergy of drug combinations in organoids and primary cells from murine tumors. [PDF]

STAR Protoc
Eisenbarth D, Ku B, Lim DS.
europepmc   +1 more source

Bayesian Dose Finding in Oncology For Drug Combinations by Copula Regression [PDF]

, 2009
Guosheng Yin, Ying Yuan
openalex   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

The first-in-Africa ex vivo drug sensitivity testing platform identifies novel drug combinations for South African leukaemia patient cohort. [PDF]

Sci Rep
Kenmogne VL, Takundwa MM, Nweke EE, Monchusi B, Dube P, Maher H, Du Toit J, Philip-Cherian V, Fru PN, Thimiri Govinda Raj DB.   +9 more
europepmc   +1 more source

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard, Lars Fredrik Fjæra, Camilla Hanquist Stokkevåg, Perry Johnson, Mark Artz, Nancy Price Mendenhall, Curtis Bryant, Ludvig Paul Muren   +7 more
wiley   +1 more source

Predicting effective drug combinations for cancer treatment using a graph-based approach. [PDF]

Synth Syst Biotechnol
Wang Q, Liu X, Yan G.
europepmc   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Syn-COM: A Multi-Level Predictive Synergy Framework for Innovative Drug Combinations. [PDF]

Pharmaceuticals (Basel)
Shi Y, Liu J, Guan S, Wang S, Yu C, Yu Y, Li B, Zhang Y, Yang W, Wang Z.   +9 more
europepmc   +1 more source

Thermal, cardiorespiratory and cortisol responses of impala (Aepyceros melampus) to chemical immobilisation with 4 different drug combinations

, 2008
Leith C. R. Meyer, Robyn S. Hetem, Linda G. Fick, A. Matthee, Duncan Mitchell, Andrea Fuller   +5 more
openalex   +2 more sources