Results 71 to 80 of about 2,669,018 (297)

Drug targeting to tumors using HPMA copolymers [PDF]

, 2009
Copolymers based on N-(2-hydroxypropyl)methacrylamide (HPMA) are prototypic and well-characterized polymeric drug carriers that have been broadly implemented in the delivery of anticancer agents.
Dep Farmaceutische wetenschappen, Lammers, T.G.G.M., Advanced drug delivery systems/drug targeting   +2 more
core   +1 more source

Species-specific activity of antibacterial drug combinations [PDF]

, 2018
The spread of antimicrobial resistance has become a serious public health concern, making once-treatable diseases deadly again and undermining the achievements of modern medicine1,2.
André Mateus, Banzhaf, Manuel; id_orcid, Ezraty, Benjamin, Anja Telzerow, Zietek, M., Py, B., Foerster, S., Joel Selkrig, Py, Béatrice, Huth, E., Telzerow, Anja, Selkrig, J., Emily Huth, Typas, Athanasios, Ana Rita Brochado, Sunniva Foerster, Natalie Ng, Stephan Göttig, Benjamin Ezraty, Savitski, Mikhail, Jordi Zamarreño Beas, Béatrice Py, Förster, Sunniva, Telzerow, A., Brochado, Ana Rita, Ng, N., Athanasios Typas, Göttig, S., Zietek, Matylda, Matylda Zietek, Ng, Natalie, Barras, Frédéric, Peer Bork, Savitski, M.M., Bork, Peer, Selkrig, Joel, Bobonis, J., Jacob Bobonis, Typas, A., Manuel Banzhaf, Zamarreño Beas, J., Bork, P., Bassler, Stefan, Göttig, Stephan, Stefan Bassler, Mateus, André, Banzhaf, Manuel, Mikhail M. Savitski, Brochado, A.R., Zamarreño Beas, Jordi, Bassler, S., Bobonis, Jacob, Ezraty, B., Huth, Emily, Barras, F., Banzhaf, M., Mateus, A., Frédéric Barras, Foerster, Sunniva, Savitski, Mikhail M   +59 more
core   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules [PDF]

Pharmaceuticals, 2018
Schistosomiasis is a major neglected tropical disease. Control of schistosomiasis currently relies on a single drug, praziquantel, and despite its efficacy against the all schistosome species that parasitize humans, it displays some problematic drawbacks and alone is ineffective in counteracting adverse pathologies associated with infection.
Maria João Gouveia, Paul J. Brindley, Fátima Gärtner, José M. Correia da Costa, Nuno Vale   +4 more
openaire   +4 more sources

Three drug combinations for late-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Uganda. [PDF]

, 2006
OBJECTIVES: Our objective was to compare the efficacy and safety of three drug combinations for the treatment of late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Louga, Albino, Fogg Carole, Louga Albino, Ghabri, S, Piola, P, Piola, Patrice, Balasegaram, M, Checchi Francesco, Balasegaram, Manica, Priotto Gerardo, Louga, A, Checchi, F, Priotto, Gerardo, Priotto, G, Erphas, Olema, Checchi, Francesco, Ghabri, Salah, Erphas, O, Balasegaram Manica, Ghabri Salah, Erphas Olema, Fogg, C, Fogg, Carole, Piola Patrice   +23 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Shortterm results of treatment of tennis elbow with antiinflammatory drugs alone or in combination with local injection of a corticosteroid and anesthetic mixture

Acta Orthopaedica et Traumatologica Turcica, 2020
Objectives: We compared the short-term results of anti-inflammatory drugs alone or in combination with local injection of a corticosteroid and anesthetic mixture in the treatment of tennis elbow.\r\nMethods: The study included 21 patients (12 males, 9 ...
Serdar Toker, Volkan Kilincoglu, Elif Aksakalli, Erim Gulcan, Korhan Ozkan   +4 more
doaj  

Observed frequencies (reporting probabilities) table for drug-drug-AE combinations.

Observed frequencies (reporting probabilities) table for drug-drug-AE combinations.
Inkyung Jung (94394), Dagyeom Jung (18397199)   +1 more
core   +1 more source