Results 271 to 280 of about 1,750,852 (307)
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Strategies for the investigation and control of process-related impurities in drug substances☆
Advanced Drug Delivery Reviews, 2007The understanding, identification, quantification and control of impurities in drug substances are essential as new molecular entities are evaluated in clinical development. As chemical processes used to produce drug substances mature from the early phases of development through registration, a concomitant maturing of process-related impurity ...
Mark D, Argentine +2 more
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National Drug Control Strategy: An Historical Analysis.
1999Abstract : America has been faced with drug use and the problems associated with harmful drugs for over a century. We have spent billions of dollars waging this war against an elusive enemy with little success. The 1998 National Drug Control Strategy is a comprehensive ten-year plan to reduce illegal drug use in the United States by 50%.
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Fabrication of Gelatin Microgels by a “Cast” Strategy for Controlled Drug Release
Advanced Functional Materials, 2012AbstractIn this paper, we propose a “casting” strategy to prepare intrinsically fluorescent, uniform and porous gelatin microgels with multi‐responsiveness. Gelatin microgels with tunable size were obtained by copying the structure of a porous CaCO3 template. The diameter of the gelatin microgels was sensitive to salt concentration and pH.
Wang, A.H. +4 more
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Strategies for prevention and control of multiple drug-resistant nosocomial infection
The American Journal of Medicine, 1981Multiple drug-resistant bacteria are common in the hospital and are often isolated from patients on admission. Spread in hospital and occasional epidemics result from transient contamination of the personnel's hands, environmental contamination and excessive use of antibiotics.
R A, Weinstein, S A, Kabins
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The National Drug Control Strategy: A Reality Check.
1997Abstract : During the past decade the United States has steadily increased its efforts to curb drug abuse and drug trafficking. Counterdrug operations have become a major area of concern in the formulation of our National Security Strategy and National Military Strategy.
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New strategies in controlling drug resistance in chronic myeloid leukemia
American Journal of Health-System Pharmacy, 2007Imatinib has been quite effective in maintaining patients with CML in the chronic phase (CP); however, some patients develop imatinib resistance. This review addresses the mechanisms underlying imatinib resistance and the strategies currently being used to overcome that resistance.Chronic myeloid leukemia (CML) is a stem cell cancer caused by BCR-ABL ...
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The National Drug Control Strategy: Is It Time for a Change?
2001Abstract : Drug abuse permeates the inner cities, affluent suburbs and rural areas of the United States. Young and old, rich and poor, educated and uneducated; no one is immune to the consequences drug abuse. The nation expends prodigious resources in combating illegal drugs, in coping with the problems compounded by drugs and the consequences of drug ...
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Reassessing Drug Control Strategy: A New Opportunity
2002Abstract : The terrorist attacks of September 11, 2001 on the United States dramatically altered the nation's strategic security environment focusing attention not only on terrorism but also creating opportunities to reexamine other aspects of our security policy.
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Targeted drug delivery strategies for precision medicines
Nature Reviews Materials, 2021Mandana T Manzari +2 more
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Strategies to access biosynthetic novelty in bacterial genomes for drug discovery
Nature Reviews Drug Discovery, 2022Jörn Piel
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