Results 131 to 140 of about 1,251,690 (298)

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

A systematic review of observational studies evaluating costs of adverse drug reactions

open access: yesClinicoEconomics and Outcomes Research, 2016
Francisco Batel Marques,1,2 Ana Penedones,1,2 Diogo Mendes,1,2 Carlos Alves,1,2 1CHAD – Centre for Health Technology Assessment and Drug Research, AIBILI – Association for Innovation and Biomedical Research on Light and Image, 2School of ...
Batel Marques F   +3 more
doaj  

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Does Medicare Part D Protect the Elderly from Financial Risk? [PDF]

open access: yes
The Medicare Modernization Act of 2003 added the Part D prescription drug benefit to the Medicare program. This addition, which became effective in 2006, increased Medicare program costs by more than 10 percent in order to provide, for the first time ...
Gary V. Engelhardt, Jonathan Gruber
core   +1 more source

Monograph no. 14: Working estimates of the social costs per gram and per user for cannabis, cocaine, opiates and amphetamines. [PDF]

open access: yes, 2007
This work represents a first step in estimating the different social costs associated with different illicit drugs. More specifically, the report sets out in detail the annual costs in Australia (circa 2004) associated with opiates, amphetamines, cocaine,
Moore, Timothy
core  

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

Comparison of Increase in Medication Costs and Medication Funding Per Capita of ‎the ‎Outpatients Insured by the Iranian Salamat Insurance in Isfahan, Iran‎

open access: yesمدیریت اطلاعات سلامت, 2016
Introduction: Medication and its cost in the country's health care system are of grave importance. Thus, the ‎aim of this study was to investigate the increase in medication costs in comparison to the ‎increase in medication funding per capita of the ...
Hosseinali Ghasemi, Mahdieh Raeeszadeh
doaj  

Does Misery Love Company? Evidence from pharmaceutical markets before and after the Orphan Drug Act [PDF]

open access: yes
With substantial fixed costs of drug development, more common conditions can support more products. If additional pharmaceutical products are beneficial, they will attract greater consumption and promote better health, e.g. greater longevity.
Frank R. Lichtenberg, Joel Waldfogel
core  

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