Results 71 to 80 of about 403,583 (300)

Clinical and Healthcare Cost Characteristics of Severe Asthma Patients with Long-Term Control on Omalizumab: A Comparative Analysis with Patients Who Switched to Other Biologics

Journal of Asthma and Allergy
Hironobu Sunadome,1,2 Hisako Matsumoto,2,3 Tadao Nagasaki,2,4 Yusuke Hayashi,2 Satoru Terada,2 Kenta Nishi,2 Natsuko Nomura,2 Mariko Kogo,2 Chie Morimoto,2 Tsuyoshi Oguma,2,5 Susumu Sato,1,2 Toyohiro Hirai2 1Department of Respiratory Care and Sleep ...
Sunadome H, Matsumoto H, Nagasaki T, Hayashi Y, Terada S, Nishi K, Nomura N, Kogo M, Morimoto C, Oguma T, Sato S, Hirai T   +11 more
doaj  

Protocol for studying the efficiency of ChemoCalc software in helping patients to understand drug treatment costs for breast cancer: A multicenter, open-label, randomized phase 2 study

, 2021
Sayaka Kuba, Hiroki Moriuchi, Kosho Yamanouchi, Kenichiro Shibata, Hiroshi Yano, Masahiro Oikawa, Shigeto Maeda, Xiangyue Meng, Michi Morita, Toshiko Hatachi, Ryota Otsubo, Megumi Matsumoto, Junya Miyamoto, Kengo Kanetaka, Hideki Taniguchi, Takeshi Nagayasu, Susumu Eguchi   +16 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cost-effectiveness of abatacept, tocilizumab and TNF-inhibitors compared with rituximab as second-line biologic drug in rheumatoid arthritis.

PLoS ONE, 2019
ObjectivesThe objective of this study was to evaluate the cost-effectiveness of abatacept, tocilizumab, and tumor necrosis factor (TNF) inhibitors as compared with rituximab in Finnish rheumatoid arthritis patients, who have previously been treated with ...
Saara Huoponen, Kalle J Aaltonen, Jaana Viikinkoski, Jarno Rutanen, Heikki Relas, Kirsi Taimen, Kari Puolakka, Dan Nordström, Marja Blom   +8 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Aquisição de medicamentos no setor público: o binômio qualidade - custo

Cadernos de Saúde Pública
No presente trabalho, os autores abordam, dentro do âmbito da administração de materiais, a aquisição e o aprovisionamento de medicamentos no setor público de saúde, discutindo as duas principais vertentes da questão: qualidade e custo.
Vera Lúcia Luiza, Claudia Garcia Serpa Osorio de Castro, Joaquim Moreira Nunes   +2 more
doaj  

Impact of a pharmacist on drug costs in a coronary care unit [PDF]

, 2001
Pritesh J. Gandhi, Brian S. Smith, Gary Tataronis, Barbara Maas   +3 more
openalex   +1 more source

Estimated Costs of Severe Adverse Drug Reactions Resulting in Hospitalization in the Veterans Health Administration [PDF]

, 2022
Sherrie L. Aspinall, Michelle Vu, Von Moore, Rong Jiang, Anthony Au, Mark Bounthavong, Peter Glassman   +6 more
openalex   +1 more source