Results 71 to 80 of about 4,128,106 (288)

Monograph no. 14: Working estimates of the social costs per gram and per user for cannabis, cocaine, opiates and amphetamines. [PDF]

open access: yes, 2007
This work represents a first step in estimating the different social costs associated with different illicit drugs. More specifically, the report sets out in detail the annual costs in Australia (circa 2004) associated with opiates, amphetamines, cocaine,
Moore, Timothy, Moore, T
core  

Urologic Cancer Drug Costs in Low- and Middle-Income Countries

open access: yesSociété Internationale d’Urologie Journal
All 189 World Bank member countries are classified by their capita gross national income into one of four income groups. In this review, we aim to explore the economic burden and management of urologic oncology conditions in low- and middle-income ...
Lan Anh S. Galloway   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Stagnation in the Drug Development Process: Are Patents the Problem? [PDF]

open access: yes
The rate of new drug development has stagnated, in spite of large increases in both private and public sector spending on biomedical research. The flip side of slower progress is higher drug costs.
Dean Baker
core  

OECD Ülkelerinde İlaç Harcamalarının Belirleyicileri

open access: yesTurkish Academic Research Review
İlaç harcamaları, 1970’ten bu yana GSYİH’nin payı olarak istikrarlı bir şekilde artmaktadır. Bununla birlikte, toplam sağlık harcamaları da artmıştır.
İsmail Biçer
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Clinical and Healthcare Cost Characteristics of Severe Asthma Patients with Long-Term Control on Omalizumab: A Comparative Analysis with Patients Who Switched to Other Biologics

open access: yesJournal of Asthma and Allergy
Hironobu Sunadome,1,2 Hisako Matsumoto,2,3 Tadao Nagasaki,2,4 Yusuke Hayashi,2 Satoru Terada,2 Kenta Nishi,2 Natsuko Nomura,2 Mariko Kogo,2 Chie Morimoto,2 Tsuyoshi Oguma,2,5 Susumu Sato,1,2 Toyohiro Hirai2 1Department of Respiratory Care and Sleep ...
Sunadome H   +11 more
doaj  

Study of Drug Utilisation and Adverse Drug Reaction Pattern of Anti-glaucoma Drugs in Patients with Primary Open Angle Glaucoma Attending the Glaucoma Clinic at a Tertiary Care Institute in Bihar, India: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Primary Open Angle Glaucoma (POAG) is a leading cause of secondary blindness, with pharmacotherapy being the mainstay of treatment. As guidelines and recommendations have evolved, so have prescribing trends.
Nitu Pandey   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Is It Possible to Have Cheaper Drugs and Preserve the Incentive to Innovate: Reforming the Drug Approval Process According to Market Principles [PDF]

open access: yes
This paper argues that drugs are expensive not because of a lack of competition among research-based pharmaceutical companies, but because of a lack of competition in the drug approval process.
Robert Sauer, Corinne Sauer
core  

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