Results 131 to 140 of about 238,633 (312)

Opium for the Masses? Conflict-Induced Narcotics Production in Afghanistan [PDF]

We show that the recent rise in Afghan opium production is caused by violent conflicts. Violence destroys roads and irrigation, crucial to alternative crops, and weakens local incentives to rebuild infrastructure and enforce law and order.
Fredrik Willumsen, Jo Thori Lind, Karl Ove Moene   +2 more
core  

Owning Marijuana [PDF]

, 2019
Legal marijuana is the fastest-growing industry in the United States. It is premised on the assumption that marijuana ownership will be protected by law. But can marijuana be owned? This Article is the first scholarship to explore the issue.
Sprankling, John G.
core   +1 more source

Drugs and extractivism: opium cultivation and drug use in the Myanmar-China borderlands

The Journal of Peasant Studies, 2023
Patrick Meehan, Seng Lawn Dan
openaire   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Icariin alleviates corneal neovascularization by regulating inflammation through inhibition of macrophage polarization and the NF-κB pathway

Journal of Translational Medicine
Background Corneal neovascularization (CorNV) is a vision-threatening complication arising from various pathological conditions. While persistent inflammation has been established as the core driver, its underlying mechanisms have not been fully ...
Longfei Zhao, Chaoqun Wei, Xinghan Guo, Xiaoxue Liu, Yifei Li, Xiaoyu Liu, Shuo Li, Zhaowei Li, Xiaoyu Liu, Liangjie Yuan, Hua Gao   +10 more
doaj   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

More structural holes, more risk? Network structure and risk perception among marijuana growers [PDF]

, 2017
Bouchard, Martin, Decorte, Tom, Malm, Aili, Vlaemynck, Marieke, Wouters, Marije   +4 more
core   +1 more source

What is new in the diagnosis of tuberculosis? Part II: Techniques for drug susceptibility testing [PDF]

, 2003
Drug susceptibility testing can be performed based on mycobacterial cultivation on solid media, either egg or agar-based. In the direct test a set of drug-containing and drug-free media is inoculated directly with concentrated specimen.
Paramasivan, C N, Ramachandran, R
core  

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

An Overview of Leishmania In Vitro Cultivation and Implications for Antileishmanial Screenings against Promastigotes

Parasitologia
The quest for new drug candidates targeting neglected parasitic diseases has become increasingly urgent over the past decades. Advancements in formulating and optimizing drug delivery systems begin with basic research, including direct assays to evaluate
Virlânio Alves de Oliveira Filho, Marcus Sávio Araujo Garcia, Leticia Bazilio Rosa, Selma Giorgio, Danilo Ciccone Miguel   +4 more
doaj   +1 more source