Results 361 to 370 of about 6,817,458 (407)
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Comprehensive Therapy, 2001
Advances in biopharmaceutical technology have spawned new drug delivery devices and mechanisms. Noninvasive methods, including iontophoresis and transmucosal drug delivery, have improved treatment of certain patient population. Their use is discussed in the following paper.
R, Zimmer, M A, Ashburn
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Advances in biopharmaceutical technology have spawned new drug delivery devices and mechanisms. Noninvasive methods, including iontophoresis and transmucosal drug delivery, have improved treatment of certain patient population. Their use is discussed in the following paper.
R, Zimmer, M A, Ashburn
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Journal of Infusion Nursing, 2007
Liposomes are composed of phospholipids, the basic components of human cell walls. Liposome encapsulation improves a medication's bioavailability, which can extend treatment effects and reduce drug dosing. The therapeutic advantages of liposomal drug delivery, such as the ability of long-circulating liposomes to accumulate preferentially at disease ...
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Liposomes are composed of phospholipids, the basic components of human cell walls. Liposome encapsulation improves a medication's bioavailability, which can extend treatment effects and reduce drug dosing. The therapeutic advantages of liposomal drug delivery, such as the ability of long-circulating liposomes to accumulate preferentially at disease ...
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Cancer, 1986
Cancer chemotherapy drugs are neither specific, i.e., they do not act exclusively on the metabolic pathways of cancer cells, nor are they targeted solely toward cancer cells. However, recent research has begun to address, in part, the latter issue. Improved delivery of chemotherapeutic agents to tumor tissue in man appears to be an achievable goal in ...
A I, Freeman, E, Mayhew
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Cancer chemotherapy drugs are neither specific, i.e., they do not act exclusively on the metabolic pathways of cancer cells, nor are they targeted solely toward cancer cells. However, recent research has begun to address, in part, the latter issue. Improved delivery of chemotherapeutic agents to tumor tissue in man appears to be an achievable goal in ...
A I, Freeman, E, Mayhew
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Advanced Drug Delivery Reviews, 1998
In recent years the nasal route has received a great deal of attention as a convenient and reliable method for the systemic administration of drugs. Although this route is currently being marketed for the systemic administration of several drugs, it has only recently been studied.
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In recent years the nasal route has received a great deal of attention as a convenient and reliable method for the systemic administration of drugs. Although this route is currently being marketed for the systemic administration of several drugs, it has only recently been studied.
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Expert Opinion on Drug Delivery, 2006
Drug delivery to the eye is hampered by anatomical factors, including the corneal epithelium, the blood-aqueous barrier and the blood-retinal barrier. This review aims to outline the major routes of ocular drug delivery, including systemic, topical, periocular and intravitreal. The pharmacokinetics, the disadvantages and the clinical relevance of these
Deepta, Ghate, Henry F, Edelhauser
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Drug delivery to the eye is hampered by anatomical factors, including the corneal epithelium, the blood-aqueous barrier and the blood-retinal barrier. This review aims to outline the major routes of ocular drug delivery, including systemic, topical, periocular and intravitreal. The pharmacokinetics, the disadvantages and the clinical relevance of these
Deepta, Ghate, Henry F, Edelhauser
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Engineering Macrophages for Cancer Immunotherapy and Drug Delivery
Advances in Materials, 2020Macrophages play an important role in cancer development and metastasis. Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 macrophages such as tumor‐associated macrophages (TAMs) promote tumor growth and invasion ...
Yuqiong Xia +5 more
semanticscholar +1 more source
2003
The central nervous system is a very attractive target for new therapeutic strategies since many genes involved in neurological diseases are known and often only local low level gene expression is required. However, as the blood brain barrier on one hand prevents some therapeutic agents given systematically from exerting their activity in the CNS, it ...
Ulrike, Blömer +2 more
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The central nervous system is a very attractive target for new therapeutic strategies since many genes involved in neurological diseases are known and often only local low level gene expression is required. However, as the blood brain barrier on one hand prevents some therapeutic agents given systematically from exerting their activity in the CNS, it ...
Ulrike, Blömer +2 more
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Current Opinion in Oncology, 2000
Intensive research efforts are now focused on the development of new strategies for more effective delivery of drugs to the central nervous system. These strategies include chemical modification of drugs, disruption of the blood-brain barrier, and utilization of alternative routes for drug delivery.
R I, Haroun, H, Brem
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Intensive research efforts are now focused on the development of new strategies for more effective delivery of drugs to the central nervous system. These strategies include chemical modification of drugs, disruption of the blood-brain barrier, and utilization of alternative routes for drug delivery.
R I, Haroun, H, Brem
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Expert Opinion on Drug Delivery, 2006
Modern drug delivery aims to develop drug delivery systems that are able to meet specific therapeutic requirements. Whereas sustained drug release aims to maintain a constant drug level within the body, pulsed drug delivery intends to release the drug rapidly within a short period of time, as a result of a biological or external trigger, after a ...
Bruno G, De Geest +4 more
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Modern drug delivery aims to develop drug delivery systems that are able to meet specific therapeutic requirements. Whereas sustained drug release aims to maintain a constant drug level within the body, pulsed drug delivery intends to release the drug rapidly within a short period of time, as a result of a biological or external trigger, after a ...
Bruno G, De Geest +4 more
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2005
Drugs, in the majority of cases, are toxic at high doses however, they must be present in the circulation for a time sufficient to reach therapeutically useful results. This is commonly achieved by repeated drug administrations, which give rise to peak and valley drug concentration. Such a method of administration has two disadvantages: on the one hand
VERONESE, FRANCESCO, CALICETI, PAOLO
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Drugs, in the majority of cases, are toxic at high doses however, they must be present in the circulation for a time sufficient to reach therapeutically useful results. This is commonly achieved by repeated drug administrations, which give rise to peak and valley drug concentration. Such a method of administration has two disadvantages: on the one hand
VERONESE, FRANCESCO, CALICETI, PAOLO
openaire +2 more sources