Results 1 to 10 of about 341,243 (219)

Astrocytes: the neglected stars in the central nervous system and drug addiction

Medical Review, 2022
With the advent of improved tools to examine the astrocytes, which have been believed to play a supportive role in the central nervous system (CNS) for years, their participation in the operation of the CNS and drug addiction was unveiled.
Chen Wenjun, Meng Shiqiu, Han Ying, Shi Jie   +3 more
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High-Frequency Deep Brain Stimulation of the Substantia Nigra Pars Reticulata Facilitates Extinction and Prevents Reinstatement of Methamphetamine-Induced Conditioned Place Preference

Frontiers in Pharmacology, 2021
Persistent and stable drug memories lead to a high rate of relapse among addicts. A number of studies have found that intervention in addiction-related memories can effectively prevent relapse.
Libo Zhang, Libo Zhang, Shiqiu Meng, Wenjun Chen, Yun Chen, Enze Huang, Guipeng Zhang, Yisen Liang, Zengbo Ding, Yanxue Xue, Yun Chen, Jie Shi, Jie Shi, Yu Shi   +13 more
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Novel role of AMPK in cocaine reinforcement via regulating CRTC1

Translational Psychiatry, 2022
Repeated cocaine exposure causes compensatory neuroadaptations in neurons in the nucleus accumbens (NAc), a region that mediates reinforcing effects of drugs.
Xiao-Xing Liu, Fang-Lin Liu, Xin Li, Tang-Sheng Lu, Yi-Xiao Luo, Min Jian, Kai Yuan, Shi-Qiu Meng, Yan-Ping Bao, Jie Shi, Lin Lu, Ying Han   +11 more
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A simplified approach for determination of urinary ethyl glucuronide by gas chromatography–mass spectrometry

Journal of Analytical Science and Technology, 2021
Urinary ethyl glucuronide (EtG), an alcohol biomarker, plays an essential role in monitoring alcohol abstinence and relapse during treatment for alcohol dependence.
Shayani Ghosh, Raka Jain, Satpal Singh, Ravindra Rao, Ashwani Kumar Mishra, Sonali Jhanjee   +5 more
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Childhood social isolation causes anxiety-like behaviors via the damage of blood-brain barrier in amygdala in female mice

Frontiers in Cell and Developmental Biology, 2022
Social interaction plays an essential role in species survival for socialized animals. Previous studies have shown that a lack of social interaction such as social isolation, especially in the early-life phase, increases the risk of developing mental ...
Xiao Wu, Xiao Wu, Zengbo Ding, Tengteng Fan, Ke Wang, Suxia Li, Jing Zhao, Weili Zhu, Weili Zhu   +8 more
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The association between neuropeptide oxytocin and neuropsychiatric disorders after orthopedic surgery stress in older patients

BMC Geriatrics, 2023
Background The health outcomes of geriatric patients exposed to surgery were found to be enhanced by social support and stress management. The aim of this study was to characterise the relationship between oxytocin and neuropsychiatric disorders after ...
Wanru Dong, Zengbo Ding, Xiao Wu, Ran Wan, Ying Liu, Liubao Pei, Weili Zhu   +6 more
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Traumatic Stress Produces Distinct Activations of GABAergic and Glutamatergic Neurons in Amygdala

Frontiers in Neuroscience, 2018
Posttraumatic stress disorder (PTSD) is an anxiety disorder characterized by intrusive recollections of a severe traumatic event and hyperarousal following exposure to the event.
Qing Fang, Qing Fang, Qing Fang, Zhe Li, Zhe Li, Geng-Di Huang, Geng-Di Huang, Huan-Huan Zhang, Huan-Huan Zhang, Ya-Yun Chen, Li-Bo Zhang, Zeng-Bo Ding, Jie Shi, Lin Lu, Lin Lu, Jian-Li Yang, Jian-Li Yang   +16 more
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Decreased Density of Perineuronal Net in Prelimbic Cortex Is Linked to Depressive-Like Behavior in Young-Aged Rats

Frontiers in Molecular Neuroscience, 2020
Perineuronal nets (PNNs) are condensed extracellular matrix (ECM) structures regulating developmental plasticity and protecting neurons against oxidative stress.
Zhoulong Yu, Zhoulong Yu, Na Chen, Na Chen, Die Hu, Die Hu, Wenxi Chen, Wenxi Chen, Yi Yuan, Yi Yuan, Shiqiu Meng, Wen Zhang, Lin Lu, Lin Lu, Lin Lu, Ying Han, Jie Shi, Jie Shi, Jie Shi   +18 more
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Predictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood

Scientific Reports, 2017
Early-life stress in adolescence has a long-lasting influence on brain function in adulthood, and it is mostly recognized as a predisposing factor for mental illnesses, such as anxiety and posttraumatic stress disorder.
Jia-Hui Deng, Wei Yan, Ying Han, Chen Chen, Shi-Qiu Meng, Cheng-Yu Sun, Ling-Zhi Xu, Yan-Xue Xue, Xue-Jiao Gao, Na Chen, Fei-Long Zhang, Yu-Mei Wang, Jie Shi, Lin Lu   +13 more
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Abuse of Pharmaceutical Drugs and Its Prevention

Fayixue Zazhi, 2021
Abuse of pharmaceutical drugs is a major public health and social problem worldwide. Mostly abused drugs mainly include opioids such as morphine, tramadol, methadone and fentanyl, sedative-hypnotics such as benzodiazepines and non-benzodiazepines, and ...
MENG Shi-qiu, SHI Jie
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