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Drug Discovery and Development
2016International ...
Lézé, Samuel, Sidi-Boumedine, Farid
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Drug development in neuropsychopharmacology
European Archives of Psychiatry and Clinical Neuroscience, 2008Personalized medicine is still in its infancy concerning drug development in neuropsychopharmacology. Adequate biomarkers with clinical relevance to drug response and/or tolerability and safety largely remain to be identified. Possibly, this kind of personalized medicine will first gain clinical relevance in the dementias. The clinical relevance of the
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Antipsychotic Drug Development
2010Schizophrenia typically manifests itself with a wide array of symptoms--positive, negative, cognitive, and affective--and may also involve neurodevelopmental and neurodegenerative aspects. Each of these symptom dimensions may be derived from pathology at one or more receptor types, localized in different regions of the brain.
Stephen M. Stahl, Dennis H. Kim
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1990
The dictionary definition of drug is ‘A medical substance used alone or as an ingredient’. Although in common usage ‘drug’ tends to be associated with illegal stimulants, I will use it here to mean any substance administered with a view to producing physiological change (excluding the basic metabolic requirements of food, water and oxygen).
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The dictionary definition of drug is ‘A medical substance used alone or as an ingredient’. Although in common usage ‘drug’ tends to be associated with illegal stimulants, I will use it here to mean any substance administered with a view to producing physiological change (excluding the basic metabolic requirements of food, water and oxygen).
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Clinical Pharmacology & Therapeutics, 2015
The concept of precision medicine has entered broad public consciousness, spurred by a string of targeted drug approvals, highlighted by the availability of personal gene sequences, and accompanied by some remarkable claims about the future of medicine. It is likely that precision medicines will require precision drug development programs.
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The concept of precision medicine has entered broad public consciousness, spurred by a string of targeted drug approvals, highlighted by the availability of personal gene sequences, and accompanied by some remarkable claims about the future of medicine. It is likely that precision medicines will require precision drug development programs.
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Biosimulation in Drug Development
2007PART I INTRODUCTION 1 Simulation in Clinical Drug Development 2 Modeling of Complex Biomedical Systems 3 Biosimulation of Drug Metabolism PART II SIMULATING CELLS AND TISSUES 4 Correlation Between In Vitro, In Situ, and In Vivo Models 5 Core-Box Modeling in the Biosimulation of Drug Action 6 The Glucose-Insulin Control System 7 Biological Rhythms in ...
Martin Bertau +2 more
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
exaly
Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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Drugs, conflict and development
International Journal of Drug Policy, 2021Jonathan Goodhand +4 more
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