Dynamics of progesterone concentration in the blood of cattle after the use of Progestamag®
Аграрная наука Евро-Северо-ВостокаThe aim of the research was to study the dynamics of progesterone concentration in the blood of heifers (n = 10) and lactating cows (n = 10) with signs of ovarian hypofunction after a single intramuscular injection of Progestamag® in a dosage of 10 ml ...
S. V. Nikolaev
doaj +1 more source
Serum levels of vancomycin: is there a prediction using doses in mg/kg/day or m2/day for neonates?
Brazilian Journal of Infectious Diseases, 2016 Coagulase-negative Staphylococcus has been identified as the main nosocomial agent of neonatal late-onset sepsis. However, based on the pharmacokinetics and erratic distribution of vancomycin, recommended empirical dose is not ideal, due to the ...
Roberta Maia de Castro Romanelli +7 more
doaj +1 more source
Cognitive dysfunction improves in systemic lupus erythematosus: Results of a 10 years prospective study [PDF]
, 2018 Objective Cognitive impairment (CI) has been described in 3–80% of Systemic lupus erythematosus (SLE) patients but only short-term studies evaluated its over-time changes, suggesting that CI is usually a stable finding. We aimed at evaluating the changes
Alessandri, Cristiano +9 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
BMC NursingBackground Screen-based simulation is a cost-effective educational modality that allows nursing students to comfortably acquire new skills as they become accustomed to digital environments.
Fatima Zahra Mahou +4 more
doaj +1 more source
The Effect of Configuration to Interaction Energy Between The Segments of Chitosan and Ascorbic Acid Molecule: Theoretical Study of Drug Release Control [PDF]
, 2015 Polymer systems plays an important role in drug delivery, which can control the time release of the drug, reduce the rate of degradation of the drug, and can reduce the toxic properties of the drug.
Hildayani, Suci Zulaikha +1 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]
, 2017 Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu +7 more
core +4 more sources
A Study to Assess the Drug Dosage Calculation Skills among Nursing Students with a View to Develop a Mobile Application on Drug Dosage Calculation in a Selected Nursing College, Greater Noida, UP. [PDF]
, 2021 Muhammad Abbas +2 more
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source