Results 121 to 130 of about 889,481 (299)
Prescribing errors : what’s the story? [PDF]
, 2001 Although prescribing errors are one of the most common causes of preventable iatrogenic injury, there have been relatively few studies of their incidence and causes. The majority of the studies that have been carried out have been based in secondary care.
Dean, Bryony
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The 1st DDIExtraction-2011 Challenge Task: Extraction of Drug-Drug Interactions from Biomedical Texts [PDF]
, 2011 Proceeding at: The 1st DDIExtraction-2011 Challenge Task: Extraction of Drug-Drug Interactions from Biomedical Texts. Took place September, 2011, in Huelva (Spain).We present an evaluation task designed to provide a framework for comparing different ...
Martínez Fernández, Paloma +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Development Strategies in Medical Education, 2017 Introduction: Considering the increasing number of drug errors, this study was conducted to investigate the factors affecting drug errors from nurses' point of view in ICU and Emergency Unite in educational hospitals of Shahrekord University of Medical ...
Milad Rezaei Farsani +1 more
doaj
Medication stewardship in the operating theatre in Malaysia: A quality improvement project
Indian Journal of AnaesthesiaBackground and Aims: A quality improvement project (‘Safe Anaesthesia for ALL-SEAL’) was implemented to reduce preventable medication errors and drug wastage in the operating theatre (OT) of a tertiary hospital.
Siti Nadzrah Yunus +5 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source