Results 41 to 50 of about 7,436,342 (338)

Redesigning the 'choice architecture' of hospital prescription charts: a mixed methods study incorporating in situ simulation testing. [PDF]

, 2014
Objectives: To incorporate behavioural insights into the user-centred design of an inpatient prescription chart (Imperial Drug Chart Evaluation and Adoption Study, IDEAS chart) and to determine whether changes in the content and design of prescription ...
Bicknell, C, Charani, E, Darzi, A, Franklin, BD, Gilchrist, M, Jabbar, A, King, D, Miller, G, Vlaev, I, Wu, Z   +9 more
core   +1 more source

PATIENT SAFETY; INTERVENTIONS TO REDUCE HOSPITAL ERRORS

Pakistan Armed Forces Medical Journal, 2020
Objective: To evaluate practices regarding prevention of factors compromising patient safety such as drug errors, never events and critical incidence reporting. Study Design: Cross-sectional study.
Sana Abbas, Amjad Akram, Syed Hamid Ali Shah, Rashid Iqbal, Beenish Abbas, Uzma Urooj   +5 more
doaj  

Applying human factors principles to alert design increases efficiency and reduces prescribing errors in a scenario-based simulation [PDF]

, 2014
OBJECTIVE: To apply human factors engineering principles to improve alert interface design. We hypothesized that incorporating human factors principles into alerts would improve usability, reduce workload for prescribers, and reduce prescribing errors.
Chen, Siying, Daggy, Joanne K., Doebbeling, Bradley N., Hawsey, Jason M., Johnson, Elizabette G., McAnas, M. Sue, Melton, Brittany L., Puleo, Anthony G., Russ, Alissa L., Russell, Scott A., Saleem, Jason J., Spina, Jeffrey R., Weiner, Michael, Zillich, Alan J.   +13 more
core   +1 more source

DDIEM: drug database for inborn errors of metabolism

Orphanet Journal of Rare Diseases, 2020
Background Inborn errors of metabolism (IEM) represent a subclass of rare inherited diseases caused by a wide range of defects in metabolic enzymes or their regulation.
Marwa Abdelhakim, Eunice McMurray, Ali Raza Syed, Senay Kafkas, Allan Anthony Kamau, Paul N Schofield, Robert Hoehndorf   +6 more
doaj   +1 more source

The incidence and types of medication errors in patients receiving antiretroviral therapy in resource-constrained settings. [PDF]

PLoS ONE, 2014
PurposeThis study assessed the incidence and types of medication errors, interventions and outcomes in patients on antiretroviral therapy (ART) in selected HIV treatment centres in Nigeria.MethodsOf 69 health facilities that had program for active ...
Kenneth Anene Agu, Dorothy Oqua, Zainab Adeyanju, Muhammadu Alfa Isah, Afusat Adesina, Samuel I Ohiaeri, Pollock N Ali, Nnenna Ekechukwu, Augustine Adah Akpakwu, Tindak Sani, Idoko Onuche Omeh, Rosalyn C King, Anthony K Wutoh   +12 more
doaj   +1 more source

Adverse Drug Events and Medication Errors in African Hospitals: A Systematic Review

Drugs - Real World Outcomes, 2017
BackgroundMedication errors and adverse drug events are universal problems contributing to patient harm but the magnitude of these problems in Africa remains unclear.ObjectiveThe objective of this study was to systematically investigate the literature on
A. Mekonnen, Tariq M. Alhawassi, A. McLachlan, Jo‐anne E. Brien   +3 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Drug related problems. Classification. Prevention methods

Кардиоваскулярная терапия и профилактика, 2023
The article describes the term “Drug related problems” and the role of its individual components. DRPs can occur at all treatment stages and can be the result of both doctor mistakes in choosing a drug and its dose, indications and contraindications, and
S. Yu. Martsevich
doaj   +1 more source