Results 131 to 140 of about 30,389 (194)

Non‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha

Allergy, EarlyView.
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka, Jitesh Chauhan, Silvia Crescioli, Sheila M. McSweeney, Amy Pope, Cheryl Gillett, Ashley Di Meo, Ioannis Prassas, Roman Laddach, Katie Stoker, Alexandra J. McCraw, Rebecca Adams, Thomas J. Tull, Nabeel Naban, Zena Willsmore, Kristina V. Semkova, Clive E. H. Grattan, John McGrath, Stephen J. Till, Christopher J. Corrigan, Rebecca Kristeleit, Sophia Tsoka, Eleftherios P. Diamandis, Katie E. Lacy, Sarah Pinder, Debra H. Josephs, James Spicer, Heather J. Bax, Sophia N. Karagiannis   +28 more
wiley   +1 more source

Clinical, Epidemiological, Virological Characteristics and Outcomes of 286 Patients Infected With Monkeypox Virus in China

Allergy, EarlyView.
Men who have sex with men (MSM), with a median age of 32 (27–37) years, from China's coastal or developed regions, are the “main mpox‐affected” population. HIV‐positive mpox patients showed more severe manifestations, with elevated aspartate transaminase and C‐reactive protein levels, reduced CD4+ T and NK (natural killer) cell counts versus HIV ...
Hankun Hu, Yang Zheng, Lianguo Ruan, Yamin Liu, Yeqing Tong, Yaokai Chen, Ke Liang, Li Zhou, Wu Chen, Yixin Hu, Wei Song, Feng Lv, Yaodong Ping, Kaiwen Fang, Nan Zhang, Hongxia Wei, Cezmi A. Akdis, Ping Ma, Yadong Gao   +18 more
wiley   +1 more source

The changing face of cancer therapeutics improved : outcome and decreased toxicity with Molecular Targeted Drugs [PDF]

, 2004
The treatment of patients with cancer has largely involved the administration of cytotoxic drugs with narrow therapeutic indices, with little selectivity for cancer cells over normal proliferating cells.
Attard, Gerhardt, De Bono, Johann S.
core  

Labial adhesions due to vulvovaginal lichen planus suspected to be caused by angiotensin II receptor blocker

IJU Case Reports
Introduction Lichenoid drug eruption, induced by gold or cardiovascular drugs, is one of the causes of lichen planus, and vulvovaginal erosive lichen planus can cause labial adhesions.
Yugo Sawada, Yasuhide Kitagawa, Atsushi Tanaka, Shunsuke Harada, Masayoshi Jimmy Nomura   +4 more
doaj   +1 more source

Oral Doxycycline Was a Safe and Feasible Treatment in Young Children With Neuroborreliosis

Acta Paediatrica, EarlyView.
ABSTRACT Aim There is limited evidence on the use of oral doxycycline in young children. We evaluated the feasibility and effectiveness of doxycycline in children under 9 years with neuroborreliosis. Methods This retrospective study included all children under 9 years of age treated for neuroborreliosis in the Capital Region of Denmark from 2019 to ...
Joakim Bloch, Lisbeth Schmidt, Nadja Vissing, Jonathan Peter Glenthøj, Birgitte Smith, Alfred Peter Born, Anja Poulsen, Anne‐Mette Lebech, Ulrikka Nygaard   +8 more
wiley   +1 more source

Safety of Advanced Combination Treatment With Selective JAK1 Inhibitors and Biological Therapies in Inflammatory Bowel Diseases: A Real World Experience

Alimentary Pharmacology &Therapeutics, EarlyView.
This multicenter study evaluates advanced combination treatment (ACT) with selective JAK1 inhibitors and biologics in 18 difficult‐to‐treat IBD patients. It shows that 77% of CD patients and 80% of UC patients achieved steroid‐free clinical remission at 3 months.
Cécile Cussac, Pauline Rivière, Romain Altwegg, Ludovic Caillo, Florian Poullenot, David Laharie, Cyrielle Gilletta, Guillaume Le Cosquer   +7 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

The challenge of policing minorities in a liberal society

, 2023
Journal of Political Philosophy, EarlyView.
Joseph Heath
wiley   +1 more source

Galcanezumab-induced fixed drug eruption

JAAD Case Reports, 2021
Skylar Klager, SM, Marina Khalil, BS, Kenneth Shulman, MD, Naveed Sami, MD   +3 more
doaj  

Clinical cues for distinguishing bullous fixed drug eruption from Stevens–Johnson syndrome: A case report

SAGE Open Medical Case Reports
This case report discusses two clinical encounters of a 62-year-old Hispanic woman initially hospitalized with suspected Stevens–Johnson syndrome, later correctly diagnosed with bullous fixed drug eruption during an outpatient visit for a similar ...
Luna Samman, Chloe Fernandez, Victoria Dukharan, Patrick Dominguez   +3 more
doaj   +1 more source