Results 231 to 240 of about 3,847,841 (356)

L‐quebrachitol Modulates the Anti‐convulsant Effects of Carbamazepine Possibly Through Voltage‐gated Sodium Channel Blocking Mechanism in Chicks: In Vivo and In Silico Studies

Brain and Behavior, Volume 15, Issue 7, July 2025.
L‐quebrachitol exhibited significant anticonvulsant effects in PTZ‐induced seizures in chicks, likely through voltage‐gated sodium channel inhibition. In vivo and in silico analyses suggest LQB may synergize with carbamazepine, offering a potential new therapeutic approach for epilepsy management. ABSTRACT Introduction L‐Quebrachitol (LQB), a naturally
Asifa Asrafi, Mohammad Aslam, Ali G. Alkhathami, Md. Sakib Hossain, Imam Hossen Rakib, Md. Sakib Al Hasan, Feroz Khan Nun, Md. Faisal Amin, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Fluoroquinolone-induced generalised fixed drug eruption: a rare clinical image. [PDF]

Pan Afr Med J
Bollineni S, Aurangabadkar G.
europepmc   +1 more source

Fixed Drug Eruption Caused by Garenoxacin: A Case Report and Literature Review. [PDF]

Cureus, 2023
Hara N, Saito-Sasaki N, Sawada Y.
europepmc   +1 more source

Drug Reaction To Ursodeoxycholic Acid: Lichenoid Drug Eruption In An Infant Using Ursodeoxycholic Acid For Neonatal Hepatitis

, 2002
Benal Büyükgebiz, Nur Arslan, Yeşim Öztürk, Cüneyt Soyal, Banu Lebe   +4 more
openalex   +1 more source

A Case Report of Generalization of Localized Actinic Granuloma, an Unusual Diffuse Presentation Not Responding to Tofacitinib

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Actinic granuloma (AG), a rare and idiopathic skin condition primarily affecting middle‐aged and elderly individuals, is known for its persistent, asymptomatic annular plaques appearing on sun‐exposed areas. This report details the case of a 48‐year‐old diabetic male farmer with a rare presentation of generalized AG. The patient's lesions were
Saman Al‐Zahawi, Alireza Ghanadan, Fatemeh Saberi   +2 more
wiley   +1 more source

Itraconazole-associated purpuric drug eruption: a rare adverse effect of a commonly prescribed drug. [PDF]

Skin Health Dis
Mathur M, Regmi S, Paudel S, Paudel S, Bhattarai N, Karki S.   +5 more
europepmc   +1 more source

Lichenoid Drug Eruption Induced by Teriflunomide. [PDF]

Ann Indian Acad Neurol, 2023
Agharbi FZ, Aasfara J, Oqbani K, Slamti K, Chiheb S.   +4 more
europepmc   +1 more source

Primary Varicella Pneumonia in an Adult With Robust Immune Status: A Case Report

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Primary varicella‐zoster virus (VZV) infection is infrequent in adults, but it causes more than 10 to 20 times the morbidity and mortality seen in healthy children and pneumonia being the most prevalent consequence. Early recognition and aggressive management of primary varicella pneumonia with antiviral therapy and supportive care is ...
Sunil Bhatta, Sukriti Pandit, Pratik Chaudhary   +2 more
wiley   +1 more source

Biopsy Confirmed Skin Drug Eruption in Setting of Ticagrelor Use. [PDF]

J Investig Med High Impact Case Rep
Steinwehr DE, Gales JM, de Leeuw AR, Anderson DS, Cunningham CR, Smith AAH.   +5 more
europepmc   +1 more source

First‐in‐human phase 1 study of KHK2455 monotherapy and in combination with mogamulizumab in patients with advanced solid tumors

Cancer, Volume 131, Issue 13, 1 July 2025.
Abstract Background Indoleamine 2,3‐dioxygenase 1 (IDO1) is a heme‐containing enzyme that degrades tryptophan (Trp) to kynurenine (Kyn), which suppresses effector T cells and reduces antitumor activity. KHK2455 is a long‐acting selective IDO1 inhibitor that blocks the heme component of the IDO holoenzyme.
Timothy A. Yap, Olivier Rixe, Capucine Baldini, Ursa Brown‐Glaberman, Sergey Efuni, David S. Hong, Christophe Massard, Jameel Muzaffar, Andreea Varga, Emrullah Yilmaz, Yuta Ikawa, Lisa H. Shiue, Yi Liu, Matthew W. Hruska, Henry Zhao, Akihiro Tokunaga, Solmaz Sahebjam   +16 more
wiley   +1 more source