Multi-View Substructure Learning for Drug-Drug Interaction Prediction [PDF]
arXiv, 2022 Drug-drug interaction (DDI) prediction provides a drug combination strategy for systemically effective treatment. Previous studies usually model drug information constrained on a single view such as the drug itself, leading to incomplete and noisy information, which limits the accuracy of DDI prediction.
arxiv
Proteomic and phosphoproteomic analysis reveals that neurokinin-1 receptor (NK1R) blockade with aprepitant in human keratinocytes activates a distinct subdomain of EGFR signaling: Implications for the anti-pruritic activity of NK1R antagonists [PDF]
, 2019 Background: Epidermal growth factor receptor (EGFR) inhibitors can cause serious cutaneous toxicities, including pruritus and papulopustular acneiform skin eruptions.
Boozalis, Emily +10 more
core +2 more sources
The Behavior of Novae Light Curves Before Eruption [PDF]
, 2009 In 1975, E. R. Robinson conducted the hallmark study of the behavior of classical nova light curves before eruption, and this work has now become part of the standard knowledge of novae. He made three points; that 5 out of 11 novae showed pre-eruption rises in the years before eruption, that one nova (V446 Her) showed drastic changes in the variability
arxiv +1 more source
Severe cutaneous reactions to drugs in the setting of a general hospital [PDF]
Anais Brasileiros de Dermatologia, 2014 BACKGROUND: Cutaneous drug reactions are frequently found. Assessing the clinical and epidemiological profile of severe forms is extremely relevant for their better recognition and management. Few studies have assessed the severe forms of cutaneous drug
Luciana Rosa Grando +2 more
doaj +1 more source
Knowledge-Driven New Drug Recommendation [PDF]
arXiv, 2022 Drug recommendation assists doctors in prescribing personalized medications to patients based on their health conditions. Existing drug recommendation solutions adopt the supervised multi-label classification setup and only work with existing drugs with sufficient prescription data from many patients.
arxiv
Therapeutic Trial of Rifabutin After Rifampicin-Associated DRESS Syndrome in Tuberculosis-Human Immunodeficiency Virus Coinfected Patients. [PDF]
, 2016 Elimination of a rifamycin from the treatment regimen for tuberculosis negatively impacts outcomes. Cross-reactivity between the rifamycins after drug eruptions is unclear.
Dheda, Keertan +6 more
core +1 more source
Prevalence of Skin Drug Eruptions in Dermatology Departments of Tehran Hospitals
مجله دانشکده پزشکی اصفهان, 2012 Background: The most common drug side effects are skin reactions. These reactions range from simple maculopapular eruptions to massive epidermal necrosis.
Saviz Saghari, Mir Hadi Aziz Jalali
doaj
Is this a simple drug eruption to be discharged?
Turkish Journal of Emergency Medicine, 2016 ‘Erythema Multiforme associated with Phenytoin And Cranial radiation Therapy’ (EMPACT) is a very rare clinic situation and classified in EM-like drug reactions. It can be easily misdiagnosed as acute urticaria or drug eruption in ED. Initial symptoms may resemble a simple skin problem, but diagnosing and early hospitalization of the patients can be ...
ELMAS, Ömer Faruk +4 more
openaire +4 more sources
Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]
, 2011 Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen +3 more
core +1 more source
Ofloxacin Induced Cutaneous Reactions in Children [PDF]
Journal of Clinical and Diagnostic Research, 2015 Cutaneous adverse effects to antimicrobials are a major health problem. Though majority of them are mild and self-limiting, severe variants like Steven Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN) are not uncommon.
Yerramalli Roja Ramani +3 more
doaj +1 more source