Results 271 to 280 of about 265,822 (283)
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Preclinical Models for Evaluating Topoisomerase I-Targeted Drugs
2005Type I and II DNA topoisomerases are the targets for numerous clinically efficacious antitumor agents. Over the last decade, considerable effort has been expended in developing camptothecin (CPT) derivatives that selectively target DNA topoisomerase I (TOP-I) (1).
Clinton F. Stewart+4 more
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Applications of Preclinical MRI/MRS in the Evaluation of Drug Efficacy and Safety
2015The drug discovery process is a series of interrelated, bidirectional steps culminating in the declaration of an investigational new drug. Upon selection of a disease target and initiation of drug screening and chemistry efforts, secondary and tertiary assays to assess the efficacy and safety of potential lead candidates or develop biomarkers to ...
Lauren Keith+2 more
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Preclinical evaluation of drug effects on testicular functions
Pharmacology & Therapeutics, 1979B. Schenck, F. Neumann
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Significance of neurochemical parameters in the preclinical evaluation of neuroleptic drugs
Pharmacology & Therapeutics, 1979Antonio Groppetti+3 more
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Preclinical evaluation of flesinoxan as a potential anxiolytic and antidepressant drug
European Journal of Pharmacology, 1990Schipper Jacques+6 more
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Preclinical evaluation of anti-CD269 antibody–drug conjugates
European Journal of Cancer, 2016C. Lutz+5 more
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[Preclinical/toxicologic evaluation of drugs].
Ugeskrift for laeger, 1999Knudsen, Lisbeth E.+2 more
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Preclinical Anticancer Drug Evaluation in Human Tumor Xenografts [PDF]
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PRECLINICAL EFFICACY EVALUATION OF PROPOSED MEDICATIONS FOR DRUG ABUSE TREATMENT
Behavioural Pharmacology, 1992R L Balster, C R Schuster
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