Results 291 to 300 of about 222,974 (348)

Nanoparticle polymeric micellar paclitaxel compared with paclitaxel for advanced esophageal squamous cell carcinoma

open access: yesPrecision Medical Sciences, EarlyView.
The nanoparticle polymeric micellar paclitaxel plus nedaplatin regimen demonstrates superior efficacy and tolerable toxicities compared to the paclitaxel–nedaplatin combination as a first‐line treatment for advanced esophageal squamous cell carcinoma.
Yu‐Qing Cao   +7 more
wiley   +1 more source

Salicylic acid: a key natural foundation for next‐generation plant defense stimulators

open access: yesPest Management Science, EarlyView.
Salicylic acid is emerging as a key natural molecule in sustainable crop protection, supporting diverse strategies to stimulate and sustain plant immunity for a greener agricultural future. Abstract The field of crop protection is undergoing a major transition.
Ruth Oussou   +3 more
wiley   +1 more source

Exposure‐Efficacy Meta‐Model of Nintedanib in Adult Patients With Chronic Fibrosing Interstitial Lung Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT The tyrosine kinase inhibitor, nintedanib, reduces the rate of decline in forced vital capacity (FVC) in a comparable manner in patients with idiopathic pulmonary fibrosis (IPF), other forms of progressive pulmonary fibrosis (PPF), and systemic sclerosis‐associated ILD (SSc‐ILD).
Sonja Hartmann   +4 more
wiley   +1 more source

Population Pharmacokinetics and Exposure‐Response Model‐Based Bayesian Extrapolation of FVC‐Based Efficacy Endpoints From Adults to Pediatric Patients Receiving Nintedanib

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Nintedanib reduces the rate of decline in forced vital capacity (FVC) in adult patients with idiopathic pulmonary fibrosis (IPF), chronic progressive‐fibrosing interstitial lung diseases (ILDs) and systemic sclerosis‐associated ILD (SSc‐ILD).
Sonja Hartmann   +4 more
wiley   +1 more source

PS49. Shifted Circadian Phase in Manic Episode was Returned to Normal after Treatment in Bipolar Disorder [PDF]

open access: yes, 2016
Cho, Chul-Hyun   +13 more
core  

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve   +6 more
wiley   +1 more source

Long‐term remission in gout: Challenges and future opportunities

open access: yesRheumatology &Autoimmunity, EarlyView.
Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley   +1 more source

Rapid Serological Detection of Anti‐GM‐CSF Autoantibodies in Autoimmune Pulmonary Alveolar Proteinosis Using a Novel Immunochromatographic Test

open access: yesRespirology, EarlyView.
We developed a novel ICT with high clinical performance that can distinguish APAP patients from those with other pulmonary diseases. The rapid and simple detection of GMAbs in serum provided a new practical method for the diagnosis of APAP. ABSTRACT Background and Objectives Anti‐GM‐CSF autoantibodies (GMAbs) are essential biomarkers for diagnosing ...
Chika Narita   +10 more
wiley   +1 more source
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Drug Hypersensitivity Reactions

Medical Clinics of North America, 2020
Drug hypersensitivity reactions (DHRs) may be classified based on timing (immediate vs delayed), mechanisms, and pattern of clinical manifestations. Management may include selection of alternative, non-cross reactive agents, drug allergy testing, graded challenge and/or desensitization.
Mark S, Dykewicz, Jason K, Lam
openaire   +2 more sources

Hypersensitivity drug reactions

Current Opinion in Allergy & Clinical Immunology, 2014
In this new issue of Current Opinion in Allergy and Clinical Immunology, five major areas of research in the field of hypersensitivity reactions to drugs in the past year are reviewed. The manuscript of Blanca-Lopez et al.[1] is devoted to hypersensitivity reactions to NSAIDs.
Bernard Y, Thong, Miguel, Blanca
openaire   +2 more sources

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