Results 331 to 340 of about 3,996,783 (390)

Cooperative Function of Atg8‐ and TORC1‐Mediated Activities in Yeast

open access: yesYeast, EarlyView.
The atg8Δ mutant is sensitive to rapamycin, and both lipidation‐dependent and ‐independent functions of Atg8 are necessary for survival during impaired TORC1 activity. Atg8‐ and TORC1‐mediated functions may contribute to maintaining vacuolar functions.
Yumiko Oba   +6 more
wiley   +1 more source

Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open‐Label Single‐Arm Clinical Trial

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Telogen effluvium (TE) is an acute and diffuse hair loss due to an abnormal increase in telogen hair follicles in response to external or internal factors. Recently, TE attracts global interest as a major cause of hair loss as a sequela of COVID‐19.
Manabu Ohyama   +6 more
wiley   +1 more source

Inflammatory Mechanisms of Dysmenorrhea: Novel Insights From Menstrual Effluent in an Adolescent Cohort

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine how eicosanoid levels in menstrual effluent of adolescents within 3 years of menarche relate to the severity of menstrual pain. Design Prospective cohort study. Setting Community teaching hospital. Population or Sample Adolescents within 3 years after menarche.
Chandrashekara N. Kyathanahalli   +2 more
wiley   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro‐Inflammatory Phenotype of Senescent Cells

open access: yesAging Cell, EarlyView.
As a natural senomorphic agent, PQQ targets the intracellular molecule. HSPA8 of senescent cells, resulting in significantly reduced expression of the SASP. PQQ holds prominent potential to delay chronological aging and ameliorate age‐related conditions by acting as an effective senomorphic agent.
Birong Jiang   +6 more
wiley   +1 more source

Social cognition and decision‐making in people with methamphetamine use disorder

open access: yesAddiction, EarlyView.
Abstract Background and Aims Impairments in social cognition and social decision‐making play an important role in the disease burden experienced by individuals with methamphetamine use disorder (MUD). They are also assumed to play a role in the vicious cycle of MUD development and hinder its successful psychotherapy. However, research typically focuses
Justin Mahlberg   +6 more
wiley   +1 more source

Are REM-Sleep Abnormalities in Depression more than an Epiphenomenon [PDF]

open access: yes, 1988
Berger, M.   +5 more
core  
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Drug Hypersensitivity Reactions

Emergency Medicine Clinics of North America, 2022
Drug hypersensitivity reactions are a diverse group of reactions mediated by the immune system after exposure to a drug. The Gell and Coombs classification divides immunologic DHRs into 4 major pathophysiologic categories based on immunologic mechanism. Anaphylaxis is a Type I hypersensitivity reaction that requires immediate recognition and treatment.
openaire   +3 more sources

Drug Hypersensitivity

Immunology and Allergy Clinics of North America, 2014
Before the arrival of modern pharmacotherapy, drug hypersensitivity reactions were virtually unknown. Toxicity from the many plant-, animal- and inorganic material-derived remedies must have been much more common. One famous example is the intoxications from mercury, which has been used in many ailments, but particularly for the treatment of syphilis ...
openaire   +5 more sources

Hypersensitivity to Drugs.

Archives of Internal Medicine, 1973
This book is one of a projected 250-volume encyclopedia of pharmacology published under the sponsorship of the International Union of Pharmacology. One is hard-pressed to think of a more ambitious venture in medical publishing. As might be expected of such an undertaking, those chosen to edit individual volumes and those selected to contribute chapters
  +7 more sources

Immediate Drug Hypersensitivity [PDF]

open access: possibleCurrent Allergy and Asthma Reports, 2016
Drug allergy affects a large percentage of the general population. A listed drug allergy can also have broad implications for many aspects of patient care. Here, we will review recent advances in the arena of drug allergies with a focus on antibiotics, monoclonals, NSAIDs, and chemotherapeutics.
David I. Hong, Paige G. Wickner
openaire   +2 more sources

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