Results 161 to 170 of about 112,427 (348)

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida   +7 more
wiley   +1 more source

The HLA-A*31:01 allele: influence on carbamazepine treatment

open access: yesPharmacogenomics and Personalized Medicine, 2017
Vincent Lai Ming Yip,1,2 Munir Pirmohamed1,2 1MRC Centre for Drug Safety Science, Institute of Translational Medicine, Department of Molecular and Clinical Pharmacology, University of Liverpool, 2Department of Clinical Pharmacology,The Royal Liverpool ...
Yip VLM, Pirmohamed M
doaj  

Education in Family Medicine : What has been achieved? [PDF]

open access: yes, 2012
Contents: Education... historical landmarks - Pierre Mallia; The Malta College of Family Doctors and the Royal College of General Practitioners - John V.
Agius, Dominic   +2 more
core  

Purtscher-like Retinopathy Related to Drug-induced Hypersensitivity Syndrome [PDF]

open access: bronze, 2012
Müge Çoban-Karataş   +2 more
openalex   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Beta-lactam and CMV induced drug hypersensitivity syndrome [PDF]

open access: yesClin Transl Allergy, 2014
Kasinskaite S   +3 more
europepmc   +1 more source

Cefotaxime desensitization [PDF]

open access: yes, 1993
Bogner, Johannes R.   +3 more
core   +1 more source

Drug hypersensitivity syndrome

open access: yesWorld Allergy Organization Journal, 2007
Wahjuni Husain   +3 more
openaire   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

open access: yesThe FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Severe cutaneous adverse reactions induced by targeted anticancer therapies and immunotherapies

open access: yesCancer Management and Research, 2018
Chun-Bing Chen,1–6 Ming-Ying Wu,1–4 Chau Yee Ng,1–5 Chun-Wei Lu,1–6 Jennifer Wu,1–4,6 Pei-Han Kao,1–4,6 Chan-Keng Yang,4–7 Meng-Ting Peng,4,6–7 Chen-Yang Huang,4,6–7 Wen-Cheng Chang,4,6–7 ...
Chen CB   +14 more
doaj  

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