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Antiepileptic Drug Hypersensitivity Syndrome

Epilepsia, 1998
Summary: : The antiepileptic drug hypersensitivity syndrome (AHS) is an adverse drug reaction associated with the aromatic antiepileptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), and primidone. The syndrome is defined by the triad of fever, skin rash, and internal organ involvement.
R G, Schlienger, N H, Shear
openaire   +4 more sources

Multiple drug hypersensitivity syndrome

Current Opinion in Allergy & Clinical Immunology, 2013
The multiple drug hypersensitivity syndrome (MDH) is a distinct clinical entity, different from cross-reactivity and flare-up reactions. Following its initial description in 1989 by Sullivan et al., several authors have addressed the issues surrounding this peculiar form of drug hypersensitivity.
Anca M, Chiriac, Pascal, Demoly
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Drug Hypersensitivity Syndrome

Dermatology, 1993
Some types of hypersensitivity to drugs are defined either by the generic name of the drug or descriptive terms. They are sometimes assimilated to pseudolymphoma because the causative drugs are often the same, although the eruption lacks clinical and histopathological criteria of pseudolymphoma.
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Relapsing drug-induced hypersensitivity syndrome

Current Opinion in Allergy & Clinical Immunology, 2016
Purpose of review Drug-induced hypersensitivity syndrome (DIHS) is a serious adverse drug reaction with potential morbidity and mortality. ‘Flare up’ or relapses in DIHS is a rare but important feature. These relapses may occur within days to several weeks, even after discontinuation of the offending drug.
Sze-Chin, Tan, Grace Y L, Chan
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Drug Hypersensitivity Syndrome Caused by Minocycline

Journal of Cutaneous Medicine and Surgery, 2006
Background: Minocycline is a commonly prescribed drug for the treatment of acne. Its use is generally not associated with systemic side effects. Objective: To describe a case of minocycline-induced drug hypersensitivity syndrome in a 20-year-old Japanese woman. Methods and Results: Following 2 months of minocycline treatment, the patient developed skin
Daisuke, Tsuruta   +4 more
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Antiepileptic Drug-Induced Hypersensitivity Syndrome Reactions

Current Drug Safety, 2006
Host dependent idiosyncratic drug reactions, otherwise known as unpredictable type B reactions, are of a major concern in clinical practice and drug development. Hypersensitivity syndrome reactions are idiosyncratic in nature and may be induced by a variety of agents including antiepileptic drugs (AEDs). The AEDs hypersensitivity syndrome is a rare but
Norberto, Krivoy   +2 more
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Drug-Induced Hypersensitivity Syndrome in Pediatric Patients

Pediatrics, 2001
The antiepileptic hypersensitivity syndrome is a severe, multiorgan reaction to oral antiepileptics that manifests as fever, rash, lymphadenopathy, and hepatitis. This same reaction pattern also has been described following administration of a few unrelated medications.
M C, Carroll   +3 more
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Drug Hypersensitivity Syndrome Induced by Meglumine Antimoniate

The American Journal of Tropical Medicine and Hygiene, 2009
We report a case of drug hypersensitivity syndrome (drug reaction with eosinophilia and systemic symptoms [DRESS]) induced by parenteral meglumine antimoniate (Glucantime) in a 40-year-old man who traveled to Bolivia and was treated for mucocutaneous leishmaniasis.
Fakhri, Jeddi   +5 more
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Cyclosporine Treatment of Drug-Induced Hypersensitivity Syndrome

JAMA Dermatology, 2016
Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is a potentially life-threatening reaction to medications with a mortality rate up to 10%. Standard therapy involves the use of systemic corticosteroids with tapering doses extending up to 9 months after the initial ...
Mark G, Kirchhof   +2 more
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