Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
Research and Industry for Human Health Enabled by Detergent Chemistry. [PDF]
ChempluschemUrner LH.
europepmc +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Perspectives on the Influence of Pharmaceutical and MedTech Companies on Deprescribing Decisions and Conference Sponsorship: A Survey Study. [PDF]
Basic Clin Pharmacol ToxicolJungo KT +3 more
europepmc +1 more source
Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström +5 more
wiley +1 more source
Evaluating the corporate social responsibility agenda for high-cost novel therapies: roles for government and civil society. [PDF]
Health Res Policy SystWong A, Saeed G, Garner S, Kohler J.
europepmc +1 more source
The Illegal Drug Industry in Latin America: The Coca-Cocaine Commodity Value Chain [PDF]
, 2007 Menno Vellinga
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Use of a Critical Constructivist, Community-Engaged Approach to Understand Commercial Determinants of Breast Cancer: The Situational Scoping Method. [PDF]
Int J Environ Res Public HealthKearns CE.
europepmc +1 more source