Results 261 to 270 of about 2,222,749 (351)

CRESTA: a comprehensive transcriptome atlas for cellular response to external stressors. [PDF]

Nucleic Acids Res
Wang H, Mu W, Bao X, Zhang L, Xie Y, Li H, Wang K, Cao Y, Chen J, Zhan J, Li L, Shen J, Ren J, Zuo Z.   +13 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The Knowledge Connector decision support system for multiomics-based precision oncology. [PDF]

Nat Commun
Hübschmann D, Kreutzfeldt S, Roth B, Glocker K, Schoop J, Oeser L, Hausmann S, Koch C, Uhrig S, Hüllein J, Hutter B, Fröhlich M, Heilig CE, Teleanu MV, Lipka DB, Kerle IA, Baude-Müller A, Beck K, Heining C, Glimm H, Ückert F, Knurr A, Fröhling S, Horak P.   +23 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Critical evaluation of real-world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation. [PDF]

Alzheimers Dement (N Y)
Tonegawa-Kuji R, Karavani E, Danziger M, Zhang P, Hou Y, Zhou Y, Bykova M, Pieper AA, Rosen-Zvi M, Cummings J, Cheng F.   +10 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Identifying false-positive drug allergy alerts based on drug tolerance assertions: a retrospective study. [PDF]

JAMIA Open
Masud JHB, Cimino JJ, Colicchio TK.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Deliberate self-harm in adolescents with OTC-related psychiatric disorders: A study of prevalence and associated factors. [PDF]

PCN Rep
Matsumoto T, Usami T, Nishimura A, Higuchi S, Okita K, Shimane T.   +5 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source