Results 161 to 170 of about 402,598 (252)

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

open access: yesAdvanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross   +3 more
wiley   +1 more source

True Closed‐Loop Recyclable Hydrogels Enabled by Imine Boronic Ester Crosslinking

open access: yesAdvanced Materials, EarlyView.
Subtle molecular differences in imine boronic ester crosslinkers profoundly influence hydrogel properties. 2‐formylphenylboronic acid crosslinkers form previously undisclosed 3‐amino‐benzoxaborole heterocycles, enhancing elasticity despite lower crosslinking density compared to their 4‐formylphenylboronic acid counterparts.
Jenna A. King   +5 more
wiley   +1 more source

Biointegrated Battery‐Based Electroceuticals

open access: yesAdvanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou   +6 more
wiley   +1 more source

Access to health and harm reduction services during drug decriminalization in British Columbia, Canada: a mixed-method study. [PDF]

open access: yesBMC Public Health
Scher BD   +8 more
europepmc   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

open access: yesAdvanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte   +21 more
wiley   +1 more source

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