Results 81 to 90 of about 1,392,421 (263)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Multinational comparison of the detection of extended-spectrum beta-lactamase genes in healthy resident feces

Microbiology Spectrum
The spread of antimicrobial-resistant bacteria, especially in developing countries, is a critical healthcare issue. Among these, extended-spectrum beta-lactamase (ESBL)-producing bacteria are particularly concerning due to their resistance to third- and ...
Yoshimasa Yamamoto, Hoa Thi Thanh Hoang, Yen Hai Le, Cornelia Appiah-Kwarteng, Diep Thi Khong, Thang Nam Nguyen, Manuel Calvopina, Carlos Bastidas-Caldes, Nobuyuki Tetsuka, Masaki Anraku, Mayumi Yamamoto   +10 more
doaj   +1 more source

WENDI: A tool for finding non-obvious relationships between compounds and biological properties, genes, diseases and scholarly publications

Journal of Cheminformatics, 2010
Background In recent years, there has been a huge increase in the amount of publicly-available and proprietary information pertinent to drug discovery. However, there is a distinct lack of data mining tools available to harness this information, and in ...
Zhu Qian, Lajiness Michael S, Ding Ying, Wild David J   +3 more
doaj   +1 more source

The Relationship Between Pharmaceutical Services and Satisfaction of Customers Accessing Pharmacy Services in Denpasar [PDF]

, 2014
Background and purpose: Pharmacetical care has been shifted from product or drug oriented paradigm into patient oriented to ensure that every custumer will be able get the most effective medication.
Arimbawa, E. (Eka)
core  

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Meningkatkan Pemahaman Siswa Tentang Bahaya Penyalahgunaan Narkoba melalui Layanan Informasi

Indonesian Journal of Guidance and Counseling: Theory and Application, 2017
The purpose of this research to know is there any progress in understanding abaut the dangerous of drug abuse after given information. The research, which is used, is a research using one grup pre test pre test-post test design. Pre test and post test us
Primanita Aisiy Nur Habibah
doaj  

Pengaruh Kualitas Pelayanan terhadap Kepuasan Konsumen Menggunakan Jasa Apotek Fitri Temanggung [PDF]

, 2019
This study aimed to see if there are service quality affects customer satisfaction in using the services of Pharmacy Fitri Temanggung. Subjects in this study is that consumers Pharmacy Fitri Temaggung aged 18-60 years; purchase drugs at private expense ...
PRADIPTA, F. R. (FARRUK)
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Use of GLP1 receptor agonists in early pregnancy and reproductive safety: a multicentre, observational, prospective cohort study based on the databases of six Teratology Information Services

BMJ Open
Objectives Glucagon-like peptide 1 receptor agonists (GLP1-RA) are indicated for the treatment of type 2 diabetes and more recently for weight loss. The aim of this study was to assess the risks associated with GLP1-RA exposure during early pregnancy ...
Marie-Claude Addor, David Baud, Maya Berlin, Alice Panchaud, Thierry Buclin, François R Girardin, Ursula Winterfeld, Corinna Weber-Schoendorfer, Orna Diav-Citrin, Faiza Lamine, Kim Dao, Svetlana Shechtman, Reem Hegla Murad, Ariela Hazan, Jonathan L Richardson, Georgios Eleftheriou, Valentin Rousson, Leonore Diezi, David Haefliger, Ana Paula Simões-Wüst   +19 more
doaj   +1 more source

Drug Checking: A prevention measure for a heterogeneous group with high consumption frequency and polydrug use - evaluation of zurich's drug checking services

Harm Reduction Journal, 2011
Background The increasing party culture in Zurich presents new challenges, especially regarding the consumption of alcohol and so-called party drugs. Streetwork, the youth advisory service of the city of Zurich, has provided onsite and stationary Drug ...
Schaub Michael, Buecheli Alexander, Hungerbuehler Ines   +2 more
doaj   +1 more source