Results 111 to 120 of about 257,450 (291)

Soft and Stiff 3D Microstructures by Step‐Growth Photopolymerization Using a Single Photoresin and Multi‐Photon Laser Printing

Advanced Functional Materials, EarlyView.
An additive and initiator‐free photoresin based on a prepolymer decorated with photoreactive step‐growth units as crosslinkers allows for the fabrication of 3D microstructures with strongly disparate mechanical properties ranging from stiff to soft. Abstract Manufacturing three‐dimensional (3D) microstructures with multi‐material properties via two ...
Tugce Nur Eren, Jiajie Liang, Jonathan Ludwig Günter Schneider, Martin Wegener, Jens Bauer, Katharina Ehrmann, Florian Feist, Christopher Barner‐Kowollik   +7 more
wiley   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Does Public Scientific Research Complement Industry R&D Investment? The Case of NIH Supported Basic and Clinical Research and Pharmaceutical Industry R&D [PDF]

This research investigates the hypothesis that publicly funded scientific research complements private R&D investment in the pharmaceutical industry. New microlevel data on public research investment by the U.S.
Toole, Andrew A.
core  

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Defining the Effectiveness of Antimalarial Chemotherapy: Investigation of the Lag in Parasite Clearance Following Drug Administration [PDF]

, 2016
David S. Khoury, Deborah Cromer, Jörg J. Möhrle, James McCarthy, Miles P. Davenport   +4 more
openalex   +1 more source

Biodegradable and Recyclable Luminescent Mixed‐Matrix‐Membranes, Hydrogels, and Cryogels based on Nanoscale Metal‐Organic Frameworks and Biopolymers

Advanced Functional Materials, EarlyView.
The study presents biodegradable and recyclable mixed‐matrix membranes (MMMs), hydrogels, and cryogels using luminescent nanoscale metal‐organic frameworks (nMOFs) and biopolymers. These bio‐nMOF‐MMMs combine europium‐based nMOFs as probes for the status of the materials with the biopolymers agar and gelatine and present alternatives to conventional ...
Moritz Maxeiner, Julian Burkhart, Kateryna Borysova, Chiara Mazzariol, Klaus Müller‐Buschbaum   +4 more
wiley   +1 more source

Ranitidine Loaded Biopolymer Floats: Designing, Characterization, and Evaluation

Journal of Chemistry, 2017
The float formulation is a strategy to improve the bioavailability of drugs by gastroretentive drug delivery system (GRDDS). A drug delivery model based on swellable and reswellable low density biopolymers has been designed to evaluate its drug release ...
Abdul Karim, Muhammad Ashraf Shaheen, Tahir Mehmood, Abdul Rauf Raza, Musadiq Aziz, Badar Din   +5 more
doaj   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Long Lag Between Drug‐induced Parkinsonism and Idiopathic Parkinson's Disease in Idiopathic REM Sleep Behavior Disorder [PDF]

, 2017
Seyed‐Mohammad Fereshtehnejad, Benjamin Dawson, Amélie Pelletier, Jacques Montplaisir, Ronald B. Postuma   +4 more
openalex   +1 more source

Solvent‐Induced Octahedral Self‐Assembly of Prussian Blue and Its Applications in Sodium‐Ion Capacitors

Advanced Functional Materials, EarlyView.
This study investigates the stepwise assembly process of octahedral Prussian Blue (PB) particles in glycerol. Initially, smaller cubic PB nanoparticles form and interact in the solvent. Over time, these particles undergo dissolution and reassembly, leading to the formation of well‐defined octahedral structures with minimized surface energy.
Seunghye Jang, Carsten Korte, Sangmin Lee, Changshin Jo   +3 more
wiley   +1 more source