Reduced attentional blink for alcohol-related stimuli in heavy social drinkers [PDF]
Researchers have used various paradigms to show that attentional biases for substance-related stimuli are an important feature of addictive behaviours. However, it is not clear whether these attentional biases occur at the level of encoding or at later ...
De Houwer, Jan +2 more
core +1 more source
LAG-3, a type of immune checkpoint receptor protein belonging to the immunoglobulin superfamily, is confirmed to be expressed on activated immune cells, mainly including activated T cells.
Jin-Ling Huo +4 more
doaj +1 more source
FDA Disclosure of Safety and Effectiveness Data: A Legal and Policy Analysis [PDF]
Syftet med studien är att genom analys av förskollärares berättelser beskriva hur barns sociala samspel och lek kan påverkas och utvecklas. Den empiriska studien baserar sig på åtta intervjuer med förskollärare som delat med sig av sina erfarenheter i ...
Appelqvist, Madeleine +1 more
core +4 more sources
Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications. [PDF]
Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of ...
Abagyan, Ruben +3 more
core +2 more sources
Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi +59 more
core +1 more source
Research and development of mAb drugs in China: a look from policy perspectives
Background: Monoclonal antibody (mAb) drugs are increasingly important for the pharmaceutical industry across the globe. In China, mAb drug developments face many challenges.
Rong Jiang +6 more
doaj +1 more source
Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne +9 more
core +4 more sources
This study was performed to develop novel core-shell gastroretentive floating pulsatile drug delivery systems using a hot-melt extrusion-paired fused deposition modeling (FDM) 3D printing and direct compression method.
Nagi Reddy Dumpa +2 more
doaj +1 more source
Enhancement of buoyant properties of gastroretentive dosage forms through nanosponge-based formulations [PDF]
Objective(s): This study aimed to develop floating tablets of an insoluble weak acidic drug. The study protocol objective was to prepare the tablets using two forms of active pharmaceutical ingredient (API): the pure form and the modified nanosponge form.
Naga Raju Kandukoori +4 more
doaj +1 more source
Characterization of Hydration Behaviour and Modeling of Film Formulation
Hydration behavior of hydrogel-based polymeric film possesses great importance in mucosal drug delivery. Modified Lag phase sigmoid model was used for the investigation of hydration of the film. Kaolin incorporated HPMC K100LVCR (HL) and K100M (HH) films
Arunima Pramanik +4 more
doaj +1 more source

