Results 31 to 40 of about 257,450 (291)

Immobilization of Analgetic AB-101 into Calcium Alginate Gels

open access: yesEurasian Chemico-Technological Journal, 2002
A new analgetic drug AB-101 has been immobilized into Ca2+-alginate gel beads with average diameter of 1 mm. A series of the alginate gel contains with various mannuronic/guluronic (M/G) ratios has been chosen to control the diffusion of the drug ...
R.M. Iskakov   +6 more
doaj   +1 more source

Design and in vitro characterization of novel pulsatile delivery system of biguanide antidiabetic drug

open access: yesJournal of Pharmacy and Bioallied Sciences, 2020
Aim: This work shows the development of pulsatile capsular pellets of metformin hydrochloride and its characterisation. Material and Methods: The novel drug delivery system consisted of hydroxy propyl cellulose Type H.
Rahul Pandey, William Selvamurthy
doaj   +1 more source

Asset allocation, cross-class correlation and the structure of property returns [PDF]

open access: yes, 1999
Practical applications of portfolio optimisation tend to proceed on a “top down” basis where funds are allocated first at asset class level (between, say, bonds, cash, equities and real estate) and then, progressively, at sub-class level (within property
Lee, Stephen, Lizieri, Colin
core   +1 more source

Drug lag for cardiovascular drug approvals in India compared with the US and EU approvals

open access: yesIndian Heart Journal, 2013
Objective: Age-standardized burden of cardiovascular diseases is substantially higher in low and middle-income countries than in high-income countries.
Bhaven C. Kataria   +2 more
doaj   +1 more source

Bridging the new drug access gap between China and the United States and its related policies

open access: yesFrontiers in Pharmacology
Introduction: The access gap for novel pharmaceuticals between China and the developed countries is a major public health issue in China. It is crucial to understand the determinants of this gap to ensure timely access to new drugs and enhance patient ...
Xingyue Zhu, Yang Chen
doaj   +1 more source

Diffusion through the ex vivo vitreal body - bovine, porcine, and ovine models are poor surrogates for the human vitreous [PDF]

open access: yes, 2018
© 2018 The Authors. Published by Elsevier B.V.The human vitreous humour is a complex gel structure whose composition and physical properties can vary considerably from person to person and also change with age. To date, the viscoelastic properties of the
Brown, Marc   +4 more
core   +4 more sources

International comparison of availability for orphan drugs: focused on approved orphan drugs in South Korea

open access: yesJournal of Pharmaceutical Policy and Practice
Introduction: In this study, we aimed to comparatively analyse the indicators of availability to orphan drugs in South Korea, the United States of America, Europe Union, and Japan.Methods: For 169 drugs designated as orphan drugs in South Korea between ...
Eun Young Shin   +4 more
doaj   +1 more source

Lag times in the publication of network meta-analyses: a survey

open access: yesBMJ Open, 2021
Objective We assessed the extent of lag times in the publication and indexing of network meta-analyses (NMAs).Study design This was a survey of published NMAs on drug interventions.Setting NMAs indexed in PubMed (searches updated in May 2020).Primary and
Fernando Fernandez-Llimos   +5 more
doaj   +1 more source

A Note on the Trandermal Delivery of Clenbuterol [PDF]

open access: yes, 1992
A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

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