Results 31 to 40 of about 4,177,143 (225)

Effect of modification of formulation variables on physical characterization of superporouse hydrogel

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2023
Superporouse hydrogel (SPH) is widely used and investigated as a gastro retentive drug delivery system to extend drug residence time in the stomach   However, their mechanical strength represents a problem because they need to withstand the ...
Safa Mohammed Nser   +1 more
doaj   +1 more source

Reimbursement Lag of New Drugs Under Taiwan's National Health Insurance System Compared With United Kingdom, Canada, Australia, Japan, and South Korea

open access: yesClinical and Translational Science, 2020
Drug lag—delayed approval or reimbursement—is a major barrier to accessing cutting‐edge drugs. Unlike approval lag, reimbursement lag is under‐researched.
Yi‐Ru Shih   +4 more
doaj   +1 more source

Optimization of Chitosan and Cellulose Acetate Phthalate Controlled Delivery of Methylprednisolone for Treatment of Inflammatory Bowel Disease [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
Purpose: Inflammatory bowel disease (IBD) is a chronic, relapsing and often life-long disorder. The best way to tackle IBD is to develop a site targeted drug delivery. Methylprednisolone is a potent anti-inflammatory steroid.
Swati Jagdale, Apoorva Chandekar
doaj   +1 more source

The promising immune checkpoint LAG-3 in cancer immunotherapy: from basic research to clinical application

open access: yesFrontiers in Immunology, 2022
LAG-3, a type of immune checkpoint receptor protein belonging to the immunoglobulin superfamily, is confirmed to be expressed on activated immune cells, mainly including activated T cells.
Jin-Ling Huo   +4 more
doaj   +1 more source

Research and development of mAb drugs in China: a look from policy perspectives

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Background: Monoclonal antibody (mAb) drugs are increasingly important for the pharmaceutical industry across the globe. In China, mAb drug developments face many challenges.
Rong Jiang   +6 more
doaj   +1 more source

Lag Time in Diffusion-Controlled Release Formulations Containing a Drug-Free Outer Layer

open access: yesProcesses, 2022
Theoretical considerations along with extensive Monte Carlo simulations are used to calculate the lag time before the initiation of diffusion-controlled drug release in multilayer planar devices with an outer layer containing no drug.
G. Kalosakas, E. Panagopoulou
semanticscholar   +1 more source

Novel Gastroretentive Floating Pulsatile Drug Delivery System Produced via Hot-Melt Extrusion and Fused Deposition Modeling 3D Printing

open access: yesPharmaceutics, 2020
This study was performed to develop novel core-shell gastroretentive floating pulsatile drug delivery systems using a hot-melt extrusion-paired fused deposition modeling (FDM) 3D printing and direct compression method.
Nagi Reddy Dumpa   +2 more
doaj   +1 more source

Enhancement of buoyant properties of gastroretentive dosage forms through nanosponge-based formulations [PDF]

open access: yesNanomedicine Journal
Objective(s): This study aimed to develop floating tablets of an insoluble weak acidic drug. The study protocol objective was to prepare the tablets using two forms of active pharmaceutical ingredient (API): the pure form and the modified nanosponge form.
Naga Raju Kandukoori   +4 more
doaj   +1 more source

Characterization of Hydration Behaviour and Modeling of Film Formulation

open access: yesActa Chimica Slovenica, 2021
Hydration behavior of hydrogel-based polymeric film possesses great importance in mucosal drug delivery. Modified Lag phase sigmoid model was used for the investigation of hydration of the film. Kaolin incorporated HPMC K100LVCR (HL) and K100M (HH) films
Arunima Pramanik   +4 more
doaj   +1 more source

Immobilization of Analgetic AB-101 into Calcium Alginate Gels

open access: yesEurasian Chemico-Technological Journal, 2002
A new analgetic drug AB-101 has been immobilized into Ca2+-alginate gel beads with average diameter of 1 mm. A series of the alginate gel contains with various mannuronic/guluronic (M/G) ratios has been chosen to control the diffusion of the drug ...
R.M. Iskakov   +6 more
doaj   +1 more source

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