Results 51 to 60 of about 4,177,143 (225)
The work is based on pulsatile principles to deliver a programmed dose of Irbesartan, an angiotensin-II receptor antagonist for chronotherapy of hypertension induced by excessive secretion of aldosterone, thereby lower the blood pressure at early morning.
Komal Parmar +2 more
doaj +1 more source
Floating tablets of minocycline hydrochloride: Formulation, in-vitro evaluation and optimization
Current study was aimed to formulate gastroretentive floating tablets of minocycline hydrochloride with desired floating properties, desired drug release rate, its local action in stomach for treatment of H.
Ali Raza +4 more
doaj +1 more source
Japan lags behind the UK in neurological drug approvals [PDF]
Many drugs that are available in the overseas market have not yet been approved by the Ministry of Health, Labour and Welfare (MHLW) in Japan. A study of the top 100 drugs by sales in 2004 shows a 2.5-year gap between the launch dates in the UK/US and Japan [1].
Rumiko, Shimazawa, Masayuki, Ikeda
openaire +2 more sources
Purpose: To develop rotigotine-loaded implants (RI) to achieve continuous release of rotigotine for long duration for the treatment of Parkinson’s disease (PD). Methods: RI was prepared by hot-melt extrusion method using poly (lactide-co-glycolide) (PLGA)
Aiping Wang +6 more
doaj +1 more source
What is known and Objective: Concern about the drug lag, the delay in marketing approval between one country and another, for anticancer drugs has increased in Japan.
E. Kawabata-Shoda +3 more
semanticscholar +1 more source
Relatlimab, an Immune Checkpoint Inhibitor that Blocks LAG-3, the Latest Drug to be Added to the Arsenal of Systemic Therapies for Melanoma: What Does a Surgical Oncologist Need to Know? [PDF]
Alexander C. J. van Akkooi
openalex +1 more source
DRUG LAG FOR ANTIMICROBIAL AGENTS: COMPARISON OF THE US, EU AND INDIA APPROVALS
Background: Antimicrobial resistance is a global problem and the need for new antimicrobial agents is greater in both developed and developing nations.
Bhaven C Kataria +2 more
doaj
The aim of present study was to develop and evaluate time controlled release tablet of Ketoprofen intended for rheumatoid arthritis. The cardinal sign of rheumatoid arthritis are stiffness, swelling and pain of one or more joints of the body ...
P H Sharma, J. G. Avari
doaj +1 more source
Reports have indicated that approval lag for anticancer drugs between Japan and the United States has decreased. However, if this is also true for drugs used to treat minor cancers remains unknown.
Kenji Yamashita, M. Kaneko, M. Narukawa
semanticscholar +1 more source
Therapeutic potential of targeting LAG-3 in cancer
Immune checkpoint inhibitors targeting negative regulatory checkpoints including programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 have produced significant improvements in progression-free survival (PFS) and overall survival in ...
Diwakar Davar +2 more
doaj +1 more source

