Results 61 to 70 of about 4,177,143 (225)

Correction to: Lag times to steady state drug delivery by continuous intravenous infusion: direct comparison of peristaltic and syringe pump performance identifies contributions from infusion system dead volume and pump startup characteristics [PDF]

, 2022
Lauren E. Gibson, Anders S. Knudsen, David Arney, Hao Deng, Nathaniel M. Sims, Robert A. Peterfreund   +5 more
openalex   +1 more source

Effects of Formulation and Process Variables on Gastroretentive Floating Tablets with A High-Dose Soluble Drug and Experimental Design Approach

Pharmaceutics, 2018
To develop sustained release gastro-retentive effervescent floating tablets (EFT), a quality-based experimental design approach was utilized during the composing of a hydrophilic matrix loaded with a high amount of a highly water-soluble model drug ...
Prakash Thapa, Seong Hoon Jeong
doaj   +1 more source

Ternary cocktail nanoparticles for sequential chemo-photodynamic therapy

Journal of Experimental & Clinical Cancer Research, 2017
Background Previous clinical trials have already demonstrated that combinations of two or more drugs were more effective in the cancer treatment, especially sequential photodynamic design combing with sequential chemotherapy.
Li Fan, Saisai Zhao, Qian Yang, Jiali Tan, Chaojun Song, Hong Wu   +5 more
doaj   +1 more source

The Entry Lag of Innovative Drugs in Russia, 2010–2019 [PDF]

, 2021
А. А. Чапленко, G. N. Gildeeva, Vasily Vlassov   +2 more
openalex   +1 more source

Regulatory efforts to address the access gap for foreign new drugs in China: the priority review program and related policies

Global Health Research and Policy
Background China has implemented the priority review (PR) program and flexible registration requirements for new drugs with significant clinical value since 2016 to accelerate drug access.
Xingyue Zhu, Jinsui Zhang
doaj   +1 more source

HPLC Methods on Drug Analysis. Mantu K. Ghosh. Berlin: Springer-Ver-lag, 1992, 585 pp. $138.00. ISBN 3-53824-0 [PDF]

, 1993
Robert L. Fitzgerald
openalex   +1 more source

The lag time in initiating clinical testing of new drugs in combination with radiation therapy, a significant barrier to progress? [PDF]

, 2014
Philip Blumenfeld, Raphael M. Pfeffer, Zvi Symon, Robert B. Den, Adam P. Dicker, David Raben, Yaacov Richard Lawrence   +6 more
openalex   +1 more source

Clinical data required for the approval of pediatric pharmaceuticals in Japan

BMC Pediatrics
Background In Japan, the number of pharmaceuticals with pediatric indications is low, and some are approved only in Europe or the USA but not in Japan. As the approval review report by the Japanese health authority contains any detailed items considered ...
Hisamitsu Haigo, Kenji Matsuda, Mayumi Shikano   +2 more
doaj   +1 more source

A current era in pulsatile drug delivery system: Drug journey based on chronobiology

Heliyon
Almost all biological processes in the human body are regulated by circadian rhythm, which results in drastically different biochemical and physiological conditions throughout a 24 h period.
Amarjitsing Rajput, Prashant Pingale, Darshan Telange, Shubham Musale, Shailesh Chalikwar   +4 more
doaj   +1 more source

Electroencephalographic effects of ketamine on power, cross-frequency coupling and connectivity in the alpha bandwidth

Frontiers in Systems Neuroscience, 2014
Recent studies of propofol-induced unconsciousness have identified characteristic properties of electroencephalographic alpha rhythms that may be mediated by drug activity at -aminobutyric acid (GABA) receptors in the thalamus.
Stefanie eBlain-Moraes, Uncheol eLee, Seungwoo eKu, GyuJeong eNoh, George A. Mashour   +4 more
doaj   +1 more source