Results 161 to 170 of about 29,922 (309)

From a beautiful circuit to a viable therapy: Addressing the translational chasm in acupuncture-based neuromodulation. [PDF]

Proc Natl Acad Sci U S A
Huang D, Dong J.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

UiO-66(Zr) as drug delivery system for non-steroidal anti-inflammatory drugs

The toxicity for the human body of non-steroidal anti-inflammatory drugs (NSAIDs) overdoses is a consequence of their low water solubility, high doses, and facile accessibility to the population.
Wu, Yi-nan, Hidalgo-Rosa, Yoan, Escalona, Néstor, Leiva, Angel, Escalona, Nesor, Schott, Eduardo, Burboa, Pia C., Salazar, Javier, Zarate, Ximena   +8 more
core   +1 more source

Correction: The role of TGF-β1 in chronic multilobar segmental bronchial stenosis and advances in targeted drug research. [PDF]

Front Pharmacol
Wu M, Yang Q, Xie Y, Hou Y, Xue Q.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Critical processes in drug release from HPMC controlled release matrices

This study has investigated the drug release mechanisms from hydroxypropyl methylcellulose (HPMC) hydrophilic matrices. A hypothesis was developed from interpretation of a previous study that drug surface activity has an influence on drug liberation. The
Pygall, Samuel R.
core  

Hardliners and liberals unite on drugs policy [PDF]

BMJ, 1995
openaire   +1 more source

Determining ED50 of Nalbuphine for Intraoperative Analgesia in Elderly Patients Undergoing Percutaneous Kyphoplasty: A Prospective, Double-Blind, Single-Center, Dose-Finding Study. [PDF]

J Pain Res
Zhao P, Song X, Liu Y, Luo Y, Cui Z, Guo Y, Wang X, Yang J, Zhou H.   +8 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Chitosan Applied to Drug Controlled Drug Liberation: A Systematic Review

Revista Virtual de Química, 2020
Túlio Natalino de Matos, Flavio Marques Lopes, Roberta Signini   +2 more
openaire   +1 more source