Results 291 to 300 of about 164,898 (351)
Overdose suicides and prescription drugs
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Journal of Paediatrics and Child Health, 1985
AbstractThis paper reviews epidemiological factors, drugs taken, management and outcome of 478 children admitted to the Royal Children's Hospital with drug poisoning during the 5 years 1978‐82. Accidental ingestion in young children is still common whilst self poisoning is increasing in the age group 8‐17 years.
J, Tibballs, E J, McArdle, T C, Brown
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AbstractThis paper reviews epidemiological factors, drugs taken, management and outcome of 478 children admitted to the Royal Children's Hospital with drug poisoning during the 5 years 1978‐82. Accidental ingestion in young children is still common whilst self poisoning is increasing in the age group 8‐17 years.
J, Tibballs, E J, McArdle, T C, Brown
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Critical Care Clinics, 1997
Poisoning is a common cause for intensive care unit admission for both children and adults, and most poisoning victims are effectively treated using standard decontamination measures and supportive care. For a small number of poisons, acceleration of toxin removal with hemodialysis or hemofiltration is indicated.
D D, Vernon, M C, Gleich
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Poisoning is a common cause for intensive care unit admission for both children and adults, and most poisoning victims are effectively treated using standard decontamination measures and supportive care. For a small number of poisons, acceleration of toxin removal with hemodialysis or hemofiltration is indicated.
D D, Vernon, M C, Gleich
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Pharmacokinetics of Drug Overdose
Clinical Pharmacokinetics, 1981Pharmacokinetics of drugs taken in overdose may differ from those observed following therapeutic doses. Differences are due both to dose-dependent changes and to effects of drugs or pathophysiological consequences of the overdose on kinetics. Dose-dependent changes in rate and extent of absorption, bioavailability (saturation of first-pass metabolism),
J, Rosenberg, N L, Benowitz, S, Pond
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Pharmacokinetics of Drugs in Overdose
Clinical Pharmacokinetics, 1992The pharmacokinetics of drugs may be altered following an overdose. The degree of absorption depends on the physical characteristics of the drug; the rate of dissolution may delay or broaden peak serum concentrations. The pathophysiological effects of a drug may also limit or augment absorption.
Y J, Sue, M, Shannon
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Pharmacokinetics of Drug Overdose
Clinics in Laboratory Medicine, 1990Drugs ingested in overdose can have altered pharmacokinetics of absorption, distribution, and elimination. The pathophysiologic consequences of overdose can also change a drug's pharmacokinetic properties. Many toxicologic interventions are based on modifying the drug's pharmacokinetics (e.g., impairing absorption or enhancing elimination).
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Hemoperfusion in Drug Overdose
JAMA: The Journal of the American Medical Association, 1978Accidental or intentional drug or poison intoxication is a serious medical problem in the United States and Europe. Self-poisoning accounts for approximately 20% of all medical emergency admissions to hospitals in the United Kingdom. In the United States, there are about 2 million poisonings each year, with 400 deaths in children.
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Overdoses of psychotherapeutic drugs
Clinical Pharmacology & Therapeutics, 1966Widespread use of the newer central nervous system depressants and stimulants has resulted in many instances of overdoses, either accidentally by children or purposely by adults. While many of the general principles of treatment of poisoning with these drugs are the same as for older sedatives and stimulants, some problems are different.
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Hemoperfusion in Poisoning and Drug Overdose
2023Hemoperfusion (HP) is an extracorporeal blood purification therapy that is used to remove poisons or drugs from the body. This chapter provides a brief overview of the technical aspects and the potential indications and limitations of HP, with the focus being on the use of HP for acute poisoning cases reported from January 1, 2000, to April 30, 2022.
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The overdose of drugs in Japan
Nature, 1989The Japanese consume enormous amounts of drugs on prescription, some of which are not legally available elsewhere in the world. The reason is a defective national system for drug approval and dispensing.
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