Results 291 to 300 of about 40,019 (337)

Provocation Tests in Diagnosing Drug Hypersensitivity

Current Pharmaceutical Design, 2008
A position paper by the European Network for Drug Allergy (ENDA), the European Academy of Allergology and Clinical Immunology (EAACI) interest group on drug hypersensitivity, defines drug provocation tests (DPTs) as "the controlled administration of a drug in order to diagnose drug hypersensitivity reactions".
Philippe-Jean, Bousquet, Francesco, Gaeta, Laure, Bousquet-Rouanet, Jean-Yves, Lefrant, Pascal, Demoly, Antonino, Romano   +5 more
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Drug provocation testing: risk stratification is key

Current Opinion in Allergy & Clinical Immunology, 2019
Purpose of review This review aims to describe current best practice and recent advances in the use of risk stratification as a tool for drug provocation testing (DPT). In particular, we focus on the testing of unsubstantiated penicillin allergy labels.
Garvey, Lene H, Savic, Louise C
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Provocative tests with psychostimulant drugs in schizophrenia

Psychopharmacology, 1987
The psychotogenic effects of psychostimulant drugs have provided a major line of evidence in support of the DA hypothesis of schizophrenia. To evaluate the effects of psychostimulant (PS) drug in schizophrenia and the clinical variables which may influence their expression, we reviewed 36 studies of PS drugs in patients with schizophrenia ...
J A, Lieberman, J M, Kane, J, Alvir
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Outcomes and safety of drug provocation tests

Allergy and Asthma Proceedings, 2011
Drug provocation tests (DPTs) are considered the gold standard for identifying adverse drug reactions (ADRs). The aim of this study was to analyze DPT results and discuss severe systemic reactions associated with them. This was a retrospective analysis of 500 patients with ADRs who sought treatment and were submitted to DPTs when indicated between 2006
Aun, Marcelo Vivolo, Bisaccioni, Carla, Garro, Laila Sabino, Rodrigues, Adriana Teixeira, Kase Tanno, Luciana, Ensina, Luis Felipe Chiaverini, Kalil, Jorge, Motta, Antonio Abilio, Giavina-Bianchi, Pedro   +8 more
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Tryptase as Severity Marker in Drug Provocation Tests

International Archives of Allergy and Immunology, 2006
<i>Background:</i> In the absence of objective symptoms, it is difficult to assess an adverse reaction during drug provocation testing. We evaluated the value of serum tryptase levels to distinguish between positive, negative and, even more important, so-called ‘hysterical’ reactions (conversion symptoms).
P, Komericki, E, Arbab, R, Grims, B, Kränke, W, Aberer   +4 more
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Ninety-Eight Fixed Drug Eruptions with Provocation Tests

Dermatology, 1988
Ninety-eight patients having fixed drug eruptions were subjected to provocation tests. Cutaneous involvement was seen in 43, mucous membrane in 33 patients, while cutaneous and mucous membrane involvement was seen in 22 patients. The causative drugs were found to be trimethoprim-sulphamethoxazole (45), acetylsalicylic acid (24), hyoscine butylbromide ...
A J, Kanwar, S C, Bharija, M, Singh, M S, Belhaj   +3 more
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Skin Testing and Drug Provocation Tests in Epidermal Necrolysis: A French Experience

The Journal of Allergy and Clinical Immunology: In Practice, 2022
There are limited data on the use of skin testing, other than patch testing, and challenges in the evaluation of epidermal necrolysis (EN), including Stevens-Johnson syndrome and toxic epidermal necrolysis.To report a French multicenter experience in skin testing and challenges in EN, and investigate the factors associated with tests' positivity.All ...
Staumont-Salle, Delphine, Dezoteux, Frederic, Soria, Angele, Barbaud, Annick, Valeyrie-Allanore, Laurence, Tétart, Florence, Bellon, Nathalia, Lebrun-Vignes, Bénédicte, Gener, Gwendeline, Paul, Muriel, Ingen-Housz-Oro, Saskia, Assier, Haudrey, Roux, Camille, Ben Said, Benoit, Milpied, Brigitte, Bernier, Claire   +15 more
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Provocative (Drug) Testing in Inherited Arrhythmias

2013
Molecular genetic studies have established a link between a number of heritable channelopathies, including congenital long QT syndrome (LQTS), Brugada syndrome (BrS), and catecholaminergic polymorphic ventricular tachycardia (CPVT), and mutations in genes encoding for ion channels or other membrane components, therefore, have become a golden standard ...
Wataru Shimizu, Michael J. Ackerman
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Drug provocation tests in children: All that glitters is not gold

Pediatric Allergy and Immunology, 2023
AbstractA proper allergy work‐up, based on the gold standard drug provocation test (DPT), usually rules out suspected drug hypersensitivity in children. These tests are generally open, given their high efficiency compared with double‐blind placebo‐controlled DPTs.
Luis Moral, Francesca Mori
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Negative predictive value of drug provocation tests in children

Pediatric Allergy and Immunology, 2014
AbstractBackgroundThe negative predictive value of the drug provocation test is important for both the patient and the physician. However, in children, this predictive value is unresolved.MethodsThe study included patients who had drug provocation test with a suspected drug and was diagnosed as ‘not allergic to the drug’.
Emine D, Misirlioglu, Muge, Toyran, Murat, Capanoglu, Aysenur, Kaya, Ersoy, Civelek, Can N, Kocabas   +5 more
openaire   +2 more sources