Results 131 to 140 of about 996,854 (268)

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Adverse Drug Reaction to Linezolid in Drug-Resistant Tuberculosis: A Systematic Review. [PDF]

Med Sci (Basel)
Oktaviani E, Anggadiredja K, Amalia L.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A Case of Evolving Hepatotoxicity Following Systemic Drug Reaction to Isoniazid-Rifapentine (3HP). [PDF]

Case Reports Hepatol
Vizgan N, Martinez-Kratz J, LaBudde C, Gordon F.   +3 more
europepmc   +1 more source

Incidence and Risk Factors of Adverse Drug Reactions Related with Antimicrobials: A Single Center Study

, 2021
Yookyung Kim, Sung Eun Kim, A Jeong Kim, Min Jung Kim, Eun‐Jung Cho, Sungyun Suh, Yoonsook Cho, Dong-Eun Lee, Eun Hwa Choi, Hye‐Ryun Kang, Ju‐Yeun Lee   +10 more
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Adverse drug reaction profiles of histone deacetylase inhibitors. [PDF]

Sci Rep
Begum R, Parsons JL, Jones AM.
europepmc   +1 more source

Case Report: Cross-reaction of phencyclidine in immunochromatographic tests for rapid drug detection using in silico analysis for investigation

Marcelo Henrique Santana Nascimento, Leonardo Corrêa Cardoso, Rachel Santos, Miguel Roehrs, Sarah Eller, Tiago Franco de Oliveira, André Valle de Bairros   +6 more
openalex   +1 more source

Epidemiological Studies of Adverse Drug Reactions

, 1965
Larry G. Seidl, George F. Thornton, Leighton E. Cluff   +2 more
openalex   +2 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source