Results 11 to 20 of about 9,770,479 (402)

Population Pharmacokinetics and Dose Optimization of Ceftazidime and Imipenem in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pharmaceutics, 2021
Background: Ceftazidime and imipenem have been increasingly used to treat Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) due to their extended-spectrum covering Pseudomonas aeruginosa.
Thu-Minh Nguyen, Thu-Hue Ngo, Anh-Quan Truong, Dinh-Hoa Vu, Dinh-Chi Le, Ngan-Binh Vu, Tuyet-Nga Can, Hoang-Anh Nguyen, Thu-Phuong Phan, Françoise Van Bambeke, Céline Vidaillac, Quy-Chau Ngo   +11 more
doaj   +1 more source

Apigenin reduces the suppressive effect of exosomes derived from irritable bowel syndrome patients on the autophagy of human colon epithelial cells by promoting ATG14

World Journal of Surgical Oncology, 2023
Background Inflammatory bowel disease (IBS) is a chronic disorder of the gastrointestinal tract. Exosomes have been involved in various pathological processes including IBS. Apigenin has been reported to suppress inflammatory bowel disease (IBS). However,
Rui Fu, Saiyue Liu, Mingjin Zhu, Jiajie Zhu, Mingxian Chen   +4 more
doaj   +1 more source

Antibacterial antibiotic-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a literature review

European Journal of Clinical Pharmacology, 2020
Drug reaction with eosinophilia and systemic symptoms syndrome (DRESS) is a delayed infrequent potentially life-threatening idiosyncratic drug reaction. Aromatic anticonvulsants and allopurinol are the most frequent causative agents.
S. Sharifzadeh, A. Mohammadpour, Ashraf Tavanaee, S. Elyasi   +3 more
semanticscholar   +1 more source

Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine

Dermatologic Therapy, 2020
A severe cutaneous drug reaction resembling acute generalized exanthematous pustulosis resulting from ingestion of hydroxychloroquine has been documented.
R. Schwartz, C. K. Janniger
semanticscholar   +1 more source

Drug-Related Deaths in China: An Analysis of a Spontaneous Reporting System

Frontiers in Pharmacology, 2022
Background: Adverse drug reactions with an outcome of death represent the most serious consequences and are inherently important for pharmacovigilance.
Haona Li, Jianxiong Deng, Peiming Yu, Xuequn Ren   +3 more
doaj   +1 more source

Adverse Drug Reaction Reporting in Ethiopia: Systematic Review

BioMed Research International, 2020
Adverse drug reactions are major global public health problems and an important cause of mortality. Problems related to medicines safety can emerge from real-life medication use due to increasing access to complex treatment of concomitant infectious and ...
Abel Demerew Hailu, S. A. Mohammed
semanticscholar   +1 more source

Drug-Induced Severe Cutaneous Adverse Reactions: Insights Into Clinical Presentation, Immunopathogenesis, Diagnostic Methods, Treatment, and Pharmacogenomics

Frontiers in Pharmacology, 2022
SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased duration of hospital stays and the associated cost burden are common issues, and in the worst-case scenario, they can result in mortality.
Therdpong Tempark, Therdpong Tempark, Shobana John, Shobana John, Pawinee Rerknimitr, Pawinee Rerknimitr, Patompong Satapornpong, Patompong Satapornpong, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem   +13 more
doaj   +1 more source

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]

, 2014
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J., Aldegunde M. J., Aldegunde M. J., Aurélien Letort, Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Chatterjee A. K., Cong Ma, De-Liang Long, Doi T., Garber S. B., Goldring P. D., Grieco P. A., Holton R. A., Holton R. A., Joëlle Prunet, Kim S.-H., Ma C., Masters J. J., Mendoza A., Morihara K., Mukaiyama T., Muller B., Muller B., Nicolaou K. C., Rémi Aouzal, Schiltz S., Scholl M., Schwab P., Swindell C. S., Wender P. A., Wender P. A., Wilde N. C., Winkler J. D., Yamazaki Y., Yared J. A., Yvon D.   +39 more
core   +3 more sources

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

Frontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li, Ting Zhang, Qinhui Liu, Jinhan He, Jinhan He   +4 more
doaj   +1 more source