Results 11 to 20 of about 1,787,106 (336)

Adverse reactions of amiodarone [PDF]

open access: yes, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo   +5 more
core   +1 more source

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

open access: yesFrontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li   +4 more
doaj   +1 more source

Study of adverse drug reactions of atypical antipsychotic drugs in the department of psychiatry in a tertiary care hospital of Assam

open access: yesOpen Journal of Psychiatry and Allied Sciences, 2017
Objective: To monitor the adverse drug reactions (ADRs) of atypical antipsychotic drugs in the outpatient department (OPD) of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam, and also to find out the causality and severity of ADRs ...
Pinaki Chakravarty   +2 more
doaj   +1 more source

Biodegradable hollow fibres for the controlled release of drugs [PDF]

open access: yes, 1988
Biodegradable hollow fibres of poly-l-lactic acid (PLLA) filled with a suspension of the contraceptive hormone levonorgestrel in castor oil were implanted subcutaneously in rats to study the rate of drug release, rate of biodegradation and tissue ...
Eenink, M.J.D.   +7 more
core   +3 more sources

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

open access: yes, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania   +19 more
core   +1 more source

The Role of Sirt6 in Obesity and Diabetes

open access: yesFrontiers in Physiology, 2018
Sirt6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It has an important role in physiological and pathological processes, regulating aging, cancer, obesity, insulin resistance ...
Jiangying Kuang   +11 more
doaj   +1 more source

Cutaneous adverse drug reactions in a tertiary teaching hospital: A prospective, observational study

open access: yesIndian Journal of Dermatology, 2021
Objective: To describe clinical patterns, identify associated drugs, and perform causality assessment of cutaneous adverse drug reactions. Materials and Methods: In this prospective, observational study, patients with signs of cutaneous drug reaction ...
Anuja Jadhav   +4 more
doaj   +1 more source

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]

open access: yes, 2014
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J.   +39 more
core   +3 more sources

Sol–gel synthesis and thermal behavior of bioactive ferrous citrate–silica hybrid materials [PDF]

open access: yes, 2018
Imbalance of the iron level in the body causes several diseases. In particular, the low level of iron, during pregnancy, is responsible for the iron deficiency anemia, and even of neurodegenerative diseases.
Catauro, M.   +3 more
core   +1 more source

Case Report: Positive Outcome of a Suspected Drug-Associated (Immune Mediated) Reaction in a 4-Year-Old Male French Bulldog

open access: yesFrontiers in Veterinary Science, 2021
Toxic epidermal necrolysis (TEN) is a rare and severe life-threatening syndrome characterized by apoptosis of keratinocytes resulting in devitalization of the epidermis affecting more than 30% of skin surface.
Line-Alice Lecru   +9 more
doaj   +1 more source

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