Results 11 to 20 of about 1,013,280 (265)

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

Frontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li, Ting Zhang, Qinhui Liu, Jinhan He, Jinhan He   +4 more
doaj   +1 more source

Valproic acid-induced eosinophilic pleural effusion: An uncommon occurrence

Lung India, 2023
A 43-year-old male using valproic acid (VA) for 2 years for seizure disorder presented with right-sided moderate pleural effusion. Pleural fluid analysis revealed exudative effusion with 42% eosinophils. There was no evidence of haemothorax, pneumothorax,
Manisha Bhardwaj, Pratibha Himral, Surender Kashyap   +2 more
doaj   +1 more source

The Role of Sirt6 in Obesity and Diabetes

Frontiers in Physiology, 2018
Sirt6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It has an important role in physiological and pathological processes, regulating aging, cancer, obesity, insulin resistance ...
Jiangying Kuang, Jiangying Kuang, Lei Chen, Lei Chen, Qin Tang, Qin Tang, Jinhang Zhang, Jinhang Zhang, Yanping Li, Yanping Li, Jinhan He, Jinhan He   +11 more
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A Case Study and a Brief Review on Dermatopathological Drug Reaction in Major Thalassemia [PDF]

Reviews in Clinical Medicine, 2023
Introduction: Thalassemia consists of a variety of genetic hemoglobinopathies. Thalassemia-major causes anemia in early age. Those suffering from thalassemia need frequent life-long blood transfusions to survive, resulting in iron overload in the body ...
Afshan Shirkavand, Leila Ataie Fashtami, Azita Azarkeivan, Zohreh Zahedi   +3 more
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Factors influencing medical staff’ s understanding of correct use for adrenaline in the treatment of severe allergic reactions: a literature review [PDF]

Xin yixue
Objective To understand the cognitive influencing factors affecting the use of epinephrine by medical staff for the treatment of serve allergic reactions and the current state of research at home and abroad.
YANG Jia, WANG Yan, DENG Li, LI Wenjun, DU Qian, LIU Songqing, XI Xin
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Predictive Performance of Bayesian Methods to Forecast Vancomycin Concentration for Therapeutic Drug Monitoring in Critically Ill Pediatric Patients

Pharmaceutics
Background: This study aimed to evaluate different Bayesian algorithms and the first-order pharmacokinetics (PK) equation approach for forecasting vancomycin concentrations in critically ill pediatric patients and to identify influencing factors. Methods:
Ha T. Pham, Cuc T. Nguyen, Tien T. N. Nguyen, Linh H. Hoang, Minh N. Tran, Thao P. Nguyen, Tuan N. Do, Ha T. H. Nguyen, Anh H. Nguyen, Phuc H. Phan, Dien M. Tran, Hoa D. Vu   +11 more
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Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol Homeostasis

Frontiers in Pharmacology, 2019
ObjectiveThe aim of this study was to investigate whether the nuclear receptor farnesoid X receptor (FXR) could regulate FNDC5/Irisin expression and the role of Irisin in hyperlipidemia and atherosclerosis in ApoE-/- mice.Methods and ResultsWe treated ...
Hong Li, Hong Li, Jing Shen, Jing Shen, Tong Wu, Tong Wu, Jiangying Kuang, Jiangying Kuang, Qinhui Liu, Shihai Cheng, Shihai Cheng, Shiyun Pu, Shiyun Pu, Lei Chen, Lei Chen, Rui Li, Rui Li, Yanping Li, Yanping Li, Min Zou, Zhiyong Zhang, Wei Jiang, Aijuan Qu, Jinhan He, Jinhan He   +24 more
doaj   +1 more source

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
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A rare adverse event of atorvastatin inducing leukocytoclastic vasculitis with ANCA‐negative (Anti‐Neutrophil cytoplasmic antibody) case report and literature review

Clinical Case Reports, 2023
Leukocytoclastic vasculitis is an entity associated with drugs, infections, cryoglobulinemia, and connective tissue diseases but can also be idiopathic, systemic, or organ localized. Moreover, LCV associated with drugs is a rare disorder.
Nehemias Guevara‐Rodriguez, Mailing Flores‐Chang, Akhila Chilakala, Jose Contreras, Paula Perdomo, Gandrabur Liliya   +5 more
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When Common Medications Trigger a Rare Reaction: A Review of Clinical Features, Diagnosis, and Treatment Options of DRESS Syndrome

Journal of Education, Health and Sport, 2023
Introduction and purpose: Drug-induced reaction with eosinophilia and systemic symptoms (DRESS) is a severe, life-threatening systemic drug reaction.
Aleksandra Hajduk, Łukasz Mrozek, Konrad Klocek, Bartosz Kostecki, Aleksander Jurek, Maciej Zwolski, Zuzanna Szumlas, Krzysztof Puchalski   +7 more
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