Drug-related problems with special emphasis on drug : drug interactions
The aim of this thesis was to address some aspects of drug related problems with special regard to drug-drug interactions. In paper I we aimed to describe the scenario and frequency of drug-related problems (DRPs) in in-patients and to determine whether a pharmacotherapeutic advisory intervention aiming at reducing DRPs could affect rates of re ...
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Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
Home medication review and drug-related problems in patients with chronic diseases at primary health centers in Yogyakarta, Indonesia: A cross-sectional multicenter study. [PDF]
Ningrum VDA +7 more
europepmc +1 more source
Drug related problems: definitions and classification.
van den Bemt, P.M.L.A., Egberts, A.C.G.
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The interfacial stability and activity of Ni‐Fe‐based AEMWE anodes can be directly enhanced by operando voltage‐cycling in a FeOOH‐containing electrolyte. This process simultaneously induces Ni oxidation and Fe incorporation, forming an integrated, porous (Fe, Ni)OOH layer with high conductivity and durability.
Euntaek Oh +10 more
wiley +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Antihypertensive drug-related problems in Vietnamese ambulatory care. [PDF]
Nguyen HH, Vu LAT, Tran MH, Pham HT.
europepmc +1 more source
Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang +12 more
wiley +1 more source
Exploring the effect of training community pharmacy staff in mentalization-based communication on recognizing patients' drug related problems: an uncontrolled pre-post intervention study in Denmark and the Netherlands. [PDF]
van Loon E +8 more
europepmc +1 more source
Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source

