Results 321 to 330 of about 3,896,424 (394)

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Drug Repurposing in Glioblastoma Using a Machine Learning-Based Hybrid Feature Selection Approach. [PDF]

Int J Mol Sci
Tasci E, Camphausen K, Krauze AV.
europepmc   +1 more source

Managing the meniscus Part 2: Traumatic tear patterns, biologic augmentation, transplantation, innovation and future research

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Acute, traumatic meniscus tears are common and should be repaired whenever possible. However, the biological age of the patient, along with the specific tear morphology, may significantly influence the selection of the repair technique, expected clinical outcomes and the postoperative rehabilitation protocol.
Armin Runer, Matthew P. Kolevar, Ehab M. Nazzal, Jonathan D. Hughes, Sebastian Kopf, Aaron J. Krych, Michael T. Hirschmann, Robert F. LaPrade, Alan Getgood, Tim Spalding, Robert Prill, Maria Tuca, Matthieu Ollivier, Sebastian Siebenlist, Sachin Tapasvi, Volker Musahl   +15 more
wiley   +1 more source

Src and Abl as Therapeutic Targets in Lung Cancer: Opportunities for Drug Repurposing. [PDF]

Pharmaceuticals (Basel)
Ramos R, Sousa C, Vale N.
europepmc   +1 more source

The Impact of Estrogen on Stromal Elements in the Proximal Airway in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
ABSTRACT Objectives Idiopathic subglottic stenosis (iSGS) is an unexplained fibrosis of the proximal airway that predominantly impacts Caucasian women. Clinically, premenopausal patients suffer from higher recurrence rates, potentially implicating ovarian hormone 17B‐estradiol (E2) in disease pathogenesis.
Emily L. Mace, Evan Clark, Edward Talatala, Maxim Litvak, Matthew A. Buendia, Yash A. Choksi, Hongmei Wu, Yueli Zhang, Alexander Hillel, Sam Collins, Quanhu Sheng, Jing Yang, Jason Park, Alexander Gelbard   +13 more
wiley   +1 more source

Network-Medicine-Guided Drug Repurposing for Alzheimer's Disease: A Multi-Dimensional Systems Pharmacology Approach. [PDF]

Int J Mol Sci
Akgüller Ö, Balcı MA, Cioca G.
europepmc   +1 more source

Meta-Analysis and Topological Perturbation in Interactomic Network for Antiopioid Addiction Drug Repurposing. [PDF]

J Chem Inf Model
Zhang C, Cottrell S, Jones B, Zhu Y, Qiu H, Zhang B, Zhou T, Jiang J.   +7 more
europepmc   +1 more source

Neural Vulnerabilities in Glioblastoma: Rethinking Therapy Through Neuroactive Drug Repurposing. [PDF]

Brain Tumor Res Treat
Colobon PO, Lee S.
europepmc   +1 more source

Gut Microbiota and Type 2 Diabetes: Genetic Associations, Biological Mechanisms, Drug Repurposing, and Diagnostic Modeling. [PDF]

Int J Mol Sci
Jin X, Chen X, Chen H, Hong X.
europepmc   +1 more source

Preliminary assessment of drug repurposing against virus-associated primary effusion lymphoma. [PDF]

J Microbiol Biol Educ
Plaza D, Chefitz G, McKiernan ER, Sandler SE, Levrero C, Kim K, Germano ER, Braner S, Ariyan LA, Miranda JL.   +9 more
europepmc   +1 more source