Results 91 to 100 of about 592,323 (309)

Engineering the Link: From Genome Interaction Maps to Functional Insight

Advanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann, Dominik Niopek   +5 more
wiley   +1 more source

Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]

, 2017
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània, Franco García, María Lourdes, Lorenzetti, Alice, Marquez, Yolanda, Puiggalí Bellalta, Jordi, Turón Dols, Pau, Valle Mendoza, Luis Javier del   +6 more
core   +2 more sources

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

Advanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel, Lea Dierker, Antoine Eyram Kwame, Kim Nora Wagner, Jonas J. Unterholzner, Jan‐Henning Dirks, Dorothea Brüggemann   +6 more
wiley   +1 more source

Multi-Drug Resistance Bacterial Infections in Critically Ill Patients Admitted with COVID-19. [PDF]

Microorganisms, 2021
Pasero D, Cossu AP, Terragni P.
europepmc   +1 more source

Defence against bacterial drug resistance. [PDF]

BMJ, 1976
Everyone knows that acquired microbic resistance is the Achilles heel of chemotherapy. All living things can acquire some resistance to noxious agents-man to morphine, for instance. Bacteria are no exception: they can become more resistant in some degree even to ordinary germicides.
openaire   +2 more sources

Deciphering the Origin of Higher Shell Coordination on Single Iron Catalysts for Resilient Modulating Persulfate Oxidation Into Singlet Oxygen Pathway

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
This study reveals that higher shell S coordination can effectively modulate the spin state of FeN4 site via long‐range electronic interactions, giving rise to the oriented generation of singlet oxygen from peroxymonosulfate activation. Abstract Precise manipulation of coordination structure of single‐atom sites and establishment of schematic ...
Liang Zhang, Kai Cheng, Zhizhi Yang, Ye Zhang, Shiro Kubuki, Paul A. Bingham, Yang‐Chun Yong, Bofan Zhang, Xiaoguang Duan   +8 more
wiley   +1 more source

Editorial: Antibiotic potentiators against drug-resistant pathogens: Discovery, development and clinical applications

Frontiers in Microbiology, 2023
Bhabatosh Das, Dinesh Mahajan, Jasna Rakonjac   +2 more
doaj   +1 more source

Exploring molecular mechanisms of drug resistance in bacteria and progressions in CRISPR/Cas9-based genome expurgation solutions

Global Medical Genetics
Antibiotic resistance in bacteria is a critical global health challenge, driven by molecular mechanisms such as genetic mutations, efflux pumps, enzymatic degradation of antibiotics, target site modifications, and biofilm formation.
K.E. Vivekanandan, P. Vinoth Kumar, R.C. Jaysree, T. Rajeshwari   +3 more
doaj   +1 more source

Investigating colistin drug resistance: The role of high-throughput sequencing and bioinformatics [version 2; peer review: 2 approved]

F1000Research, 2019
Bacterial infections involving antibiotic-resistant gram-negative bacteria continue to increase and represent a major global public health concern.
Dickson Aruhomukama, Ivan Sserwadda, Gerald Mboowa   +2 more
doaj   +1 more source

Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine feces [PDF]

, 2007
The aim of this study was to assess the impact of three ampicillin dosage regimens on ampicillin resistance among Enterobacteriaceae recovered from swine feces using phenotypic and genotypic approaches.
Bibbal, Delphine, Bousquet-Mélou, Alain, Dupouy, Véronique, Fayet, O, Ferré, JP, Prère, MF, Toutain, Pierre-Louis   +6 more
core   +4 more sources