Results 121 to 130 of about 544,638 (287)

Identification of New Drug Targets in Multi-Drug Resistant Bacterial Infections [PDF]

, 2013
Abstract : We are combining two parallel efforts to explore new targets and pathways in A. baumannii. We hypothesize that two proteins involved in aromatic amino acid and metabolite biosynthesis are essential and are valid targets for development of inhibitors as potential antibiotics.
Timothy C. Umland, Thomas A. Russo, L.W. Schultz, Andrew M. Gulick   +3 more
openaire   +2 more sources

Profiling and tandem mass spectrometry analysis of aminoacylated phospholipids in Bacillus subtilis  [version 2; referees: 1 approved, 2 approved with reservations]

F1000Research, 2016
Cationic modulation of the dominantly negative electrostatic structure of phospholipids plays an important role in bacterial response to changes in the environment.
Metin Atila, Yu Luo
doaj   +1 more source

A Sustainable Biotechnology Approach for Mineral Separation

Advanced Functional Materials, EarlyView.
Silver‑binding peptides are first identified through phage‐display screening, and then engineered into multifunctional and responsive peptides or proteins. These tailored biomolecules can selectively capture and aggregate silver particles or ions from complex mixtures, enabling rapid and efficient silver separation and recovery.
Guangze Yang, Yun Liu, Shankar Raj Devkota, Yue Hui, Ruilin Zhao, Yang Li, David A. Weitz, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Biomaterials-based phototherapy for bacterial infections

Frontiers in Pharmacology
Bacterial infections and antibiotic resistance are global health problems, and current treatments for bacterial infections still rely on the use of antibiotics.
Guangzhi Wu, Zhuo Xu, Yue Yu, Minglei Zhang, Shuaishuai Wang, Shuo Duan, Xilin Liu   +6 more
doaj   +1 more source

Alanylated lipoteichoic acid primer in Bacillus subtilis [version 2; referees: 2 approved]

F1000Research, 2016
Lipoteichoic acid is a major lipid-anchored polymer in Gram-positive bacteria such as Bacillus subtilis. This polymer typically consists of repeating phosphate-containing units and therefore has a predominant negative charge.
Yu Luo
doaj   +1 more source

Supramolecular Zwitterionic Hydrogels for Information Encryption, Soft Electronics and Energy Storage at Icy Temperature

Advanced Functional Materials, EarlyView.
A series of ACHPES‐based hydrogels are developed and realizing multiple functions like anti‐fouling properties, alkali‐induced color/fluorescence‐changing ability and strain sensing. Furthermore, the hydrogels show excellent anti‐freezing performance, whose optical, mechanical and electrical properties remain stable at −47.3 °C.
Gaopeng Wang, Haochen Ni, Yifan Li, Hamdi Torun, Sherry Chen, Muhammad Wakil Shahzad, Xuehua Zhang, Si Yu Zheng, Ben Bin Xu, Jintao Yang   +9 more
wiley   +1 more source

Defense against bacterial drug resistance. [PDF]

BMJ, 1976
W. P. Ferguson, T. D. Wyatt, T. S. Wilson   +2 more
openaire   +3 more sources

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

Characterization and in vitro Analysis of Probiotic-Derived Peptides Against Multi Drug Resistance Bacterial Infections. [PDF]

Front Microbiol, 2020
Mazumdar A, Haddad Y, Sur VP, Milosavljevic V, Bhowmick S, Michalkova H, Guran R, Vesely R, Moulick A.   +8 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source