Results 171 to 180 of about 592,323 (309)
Computational framework for streamlining the success of sequential antibiotic therapy. [PDF]
Anderson A +5 more
europepmc +1 more source
Bacterial resistance to antituberculosis drugs
openaire +1 more source
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu +10 more
wiley +1 more source
Antimicrobial resistance pattern due to oxygen gap at high altitudes. [PDF]
Yang ZC, Han ZR, Li XY, Duan YB.
europepmc +1 more source
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf +5 more
wiley +1 more source
Combating <i>Klebsiella pneumoniae</i>: from antimicrobial resistance mechanisms to phage-based combination therapies. [PDF]
Ding J, Yan W, Zheng R, Ma M, Jiang L.
europepmc +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Targeted Drug Delivery Strategies in Overcoming Antimicrobial Resistance: Advances and Future Directions. [PDF]
Alidriss OM +10 more
europepmc +1 more source
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao +6 more
wiley +1 more source
Drivers of antibiotic misuse and resistance in Pakistan: a public health challenge. [PDF]
Basir S +5 more
europepmc +1 more source

